Session Details

[O3]Oral Session 3 Cancer Genetics 1

Thu. Oct 10, 2024 8:30 AM - 9:20 AM JST
Thu. Oct 10, 2024 11:30 PM - 12:20 AM UTC
Room 6(Castle, 1F)
Chairs:Makoto Hirata(National Cancer Center Hospital), Katsutoshi Oda(The University of Tokyo Hospital, Department of Clinical Genomics)

[O3-1]Analysis of Secondary Findings Related to Pathogenic BRCA1/2 Variants Identified in Comprehensive Genome Profiling

Yoshinaga Okugawa1,2, Takumi Fujiwara1, Junya Tsuboi1, Takahito Kitajima1,2, Emi Teramoto1, Maki Nakamura1, Makoto Ikejiri1, Ikuyo Mochiki1, Ryotaro Hashizume1, Hiroshi Imai1, Kaname Nakatani1, Yuji Toiyama2 (1.Department of Genomic Medicine, Mie University Hospital, Mie, Japan, 2.Department of Gastrointestinal and Pediatric Surgery)

[O3-2]Clinical outcome of returning genomic results to BRCA1 and BRCA2 pathogenic variant carriers found in general population

Yoichi Suzuki1,2, Kinuko Ohneda1, Yohei Hamanaka1,3, Takanori Ishida3, Junko Minato4, Muneaki Shimada4,5, Hiroshi Kawame6, Nobuo Fuse1,5, Fuji Nagami1,5, Masayuki Yamamoto1,5 (1.Tohoku University Tohoku Medical Megabank Organization, Sendai, Miyagi, Japan, 2.Department of Clinical Genetics, Ageo Central General Hospital, Ageo, Saitama, Japan, 3.Department of Breast and Endocrine Surgical Oncology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 4.Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 5.Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, Miyagi, Japan, 6.Department of Clinical Genetics, Jikei University Hospital, Tokyo, Japan)

[O3-3]Evaluations of secondary findings using CGP with a focus on family history in colorectal cancer

Takahito Kitajima1,2, Yoshinaga Okugawa1,2, Maki Nakamura1, Makoto Ikejiri1, Takumi Fujiwara1, Junya Tsuboi1, Ikuyo Mochiki1, Ryotaro Hashizume1, Hiroshi Imai1, Kaname Nakatani1 (1.The Department of Genomic Medicine, Mie University Hospital, 2.The Department of Gastrointestinal and Pediatric Surgery, Mie University)

[O3-4]Characterization of Clonal Hematopoiesis Associated Findings in the FoundationOne Liquid(F1L) test in Pancreatic Cancer

Manami Matsukawa1, Takashi Kubo2, Kuniko Sunami2, Takafumi Koyama3, Kazuki Sudo3,4, Satoyo Oda1,2, Noriko Tanabe1,5, Tomoko Watanabe1, Chikako Tomozawa1, Teruhiko Yoshida1, Noboru Yamamoto3, Makoto Hirata1 (1.Department of Genetic Medicine and Services, National Cancer Center, Tokyo, Japan, 2.Department of Clinical Laboratories, National Cancer Center, Tokyo, Japan, 3.Department of Experimental therapeutics, National Cancer Center, Tokyo, Japan, 4.Department of Medical Oncology, National Cancer Center, Tokyo, Japan, 5.Department of Clinical Genetics, Saitama Medical Center, Saitama, Japan)

[O3-5]Clinical profiling of postzygotic mosaicism in hereditary cancer genes: analysis of 27 individuals in 18 families

Chikako Tomozawa1, Tomoko Watanabe1, Noriko Tanabe1,2, Manami Matsukawa1, Mineko Ushiama1,3, Masahiro Gotoh3, Satoyo Oda1,4, Yasushi Goto5, Susumu Hijioka6, Mayumi Kato7, Yoshiyuki Matsui8, Chigusa Morizane6, Shiino Sho9, Shigenobu Suzuki10, Masayoshi Yamada1,11, Hiromi Sakamoto1,12, Kokichi Sugano1,13, Teruhiko Yoshida1, Makoto Hirata1 (1.Department of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan, 2.Department of Clinical Genetics, Saitama Medical Center, Saitama, Japan, 3.Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan, 4.Department of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan, 5.Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan, 6.Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan, 7.Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan, 8.Department of Urology and Retroperitoneal Surgery, National Cancer Center Hospital, Tokyo, Japan, 9.Department of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan, 10.Department of Ophthalmic Oncology, National Cancer Center Hospital, Tokyo, Japan, 11.Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan, 12.Deptartment of Biobank and Tissue Resources, National Cancer Center Research Institute, Tokyo, Japan, 13.Department of Genetic Medicine, Kyoundo Hospital, Sasaki Foundation, Tokyo, Japan)