Presentation Information
[II-TKIS-P-7]Association of a Polygenic Risk Score with Pulmonary Valve Replacement in Repaired Tetralogy of Fallot
○Takanori Suzuki1,2, Sandar Min1, Sean J Jurgens3,4, Jade Bouwmeester1, Robert Lesurf1, Alex V. Postma5,6, Gillian Blue7, David Winlaw8, Connie R Bezzina3,9, Seema Mital1,2,10 (1.Genetics and Genome Biology Program, Hospital for Sick Children, Toronto, Ontario, Canada, 2.Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada, 3.Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands, 4.Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA, 5.Department of Medical Biology, Amsterdam University Medical Center, Amsterdam, the Netherlands., 6.Department of Human Genetics, Amsterdam University Medical Center, Amsterdam, the Netherlands., 7.Heart Centre for Children, The Children's Hospital at Westmead, Sydney, NSW, Australia., 8.Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA., 9.European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart, 10.Ted Rogers Centre for Heart Research, Toronto, Ontario, Canada)
Keywords:
Tetralogy of Fallot,right ventricular remodeling,pulmonary valve replacement