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Session Details

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Program Type

Regulation of reaction field of enzyme by the control of liquid-liquid phase separation with gold nanobutterfly nanodevice<br/><br/>

Liquid-liquid phase separation(LLPS) of bio-macromolecule has gathered various attention. LLPS is a phenomenon that bio-macromolecules, such as DNA or protein form liquid phases under suitable conditions and form sphere shape reaction fields called droplets. Sophisticated behaviors of cells have been analyzed from the viewpoint of LLPS and these have caused an emergence of a new topic called “Phasing Biology". On the other hand, although versatile research has revealed the externalistic interesting phenomenon, a deep understanding of droplets themselves and how to interpret observation of droplets have tended to be left. In this symposium, we are going to clarify equivocal and/or overlooked points about phasing biology from the biological and physical scientists' opinions and discuss the topics with engineering knowledge of droplet manipulations. We aim to reinforce the fundamental parts of Phasing Biology with the integration of the multidimensional experiences both of droplet analysis and creation.

日本分子生物学会年会

The 46th Annual Meeting of the Molecular Biology Society of Japan

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1AS-02-09]Regulation of reaction field of enzyme by the control of liquid-liquid phase separation with gold nanobutterfly nanodevice

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