日本分子生物学会年会

[1AS-01-Introduction]Introduction

^○Kazuo Yamagata(Kindai University)

[1AS-01-01]Will the 28,000-year-old mammoth DNA awaken?
Recreating biological phenomena with ancient DNA, opening a new door to paleontological science

^○Tasuku Mitani(Biol. Oriented Sci. Technol., Kindai Univ.)

[1AS-01-02]Generation of transchromosomic animals with a trans-species chromosome and the application by super chromosome engineering

^○Yasuhiro Kazuki(CERC, Tottori Univ.)

[1AS-01-03]Ex-situ conservation of wildlife by genomic analysis and oocyte biobank

^○Miho Murayama, Mayko Fujihara(WRC, Kyoto Univ.)

[1AS-01-04]Understanding the ecology of endangered species based on the DNA sequences

^○Haruko Ando(National Institute for Environmental Studies)

[1AS-01-05_1P-663]Interaction analysis between algae and fish using an artificial symbiotic system

^○Yoji Okabe¹, Shoji Oda¹, Kintake Sonoike², Yayoi Inui¹, Tomoko Matsunaga¹, Shinichiro Maruyama¹, Sachihiro Matsunaga¹(1.Dept. of Integr. Bio. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2.Dept. of Biol., Dept. of Integr. Bio. Sci. and Bio. Med. Engr., Waseda Univ.)

[1AS-01-06]Induced pluripotent stem cells of endangered avian species

^○Masafumi Katayama(Bio Div, NIES)

[1AS-01-07]Producing Tokyo bittering, a small fish on the brink of extinction, from frozen cells

^○Goro Yoshizaki, Koju Yamakawa(Tokyo University of Marine Science and Technology)

[1AS-01-08]Methodology of germ cell production from pluripotent stem cells in endangered species

^○Katsuhiko Hayashi, Masafumi Hayashi(Osaka University)

[1AS-01-Conclusion]Conclusion

^○Katsuhiko Hayashi(Osaka University)

[1AS-02-Introduction]Introduction

^○Tomohiro Nobeyama(Fac. of. Pure and Appl. Sci.)

[1AS-02-01]Liquid-liquid phase separation of enzymes

^○Natsuko Miura(Dept. of Appl. Biol. Sci., Grad. Sch. of Agric., Osaka Metropolitan Univ.)

[1AS-02-02]Not a simple phase separation: Spatiotemporal patterns by reaction-diffusion coupling in artificial cells

^○Sakura Takada, Kei Fujiwara(Dept. Biosci. and Info., Keio Univ.)

[1AS-02-03]Activation of oxidoreductases by the formation of enzyme assembly

^○Tsutomu Mikawa(RIKEN BDR)

[1AS-02-04_1P-465]Independent regulation of the G1-S and G2-M transitions realized by topology of the fission yeast cell cycle network

^○Yuhei Yamauchi¹, Hironori Sugiyama², Yuhei Goto², Kazuhiro Aoki², Atsushi Mochizuki¹(1.Inst. Life Med. Sci., Kyoto Univ., 2.Q-BIO., NIBB)

[1AS-02-05]Droplet formation factors of in vitro systems

^○Chiho Watanabe(Hiroshima Univ.)

[1AS-02-06]Functional expression in artificial cell system synthesizing lipids inside membrane vesicles

^○Yutetsu Kuruma¹, Sumie Eto², Rumie Matsumura¹, Yasuhiro Shimane¹, Mai Fujimi², Samuel Berhanu², Takeshi Kasama²(1.JAMSTEC, 2.Tokyo Institute of Technology)

[1AS-02-07_1P-417]Mechanism of Golgi degradation by autophagy

^○Shinri Kitta¹, Tatsuya Kaminishi², Momoko Higashi³, Takayuki Shima², Hidetaka Kosako⁴, Tamotsu Yoshimori^2,3, Akiko Kuma²(1.Sch. of Med., Fac. of Med., Osaka Univ., 2.Dept. of Genetics, Grad. Sch. of Med., Osaka Univ., 3.Lab. of Intra. Memb. Dyna., Grad. Sch. of Front. Bio., Osaka Univ., 4.Div. of Cel. Sig., Inst. of Adv. Med. Sci., Tokushima Univ.)

[1AS-02-08]Understanding protein droplets as a site of amyloid fibril formation

^○Eri Chatani¹, Yumiko Ohhashi^1,2, Mao Fukuyama³(1.Dept. of Chem., Grad. Sch. of Sci., Kobe Univ., 2.CBC, Tokyo Tech., 3.IMRAM, Tohoku Univ.)

[1AS-02-09]Regulation of reaction field of enzyme by the control of liquid-liquid phase separation with gold nanobutterfly nanodevice

^○Tomohiro Nobeyama(Fac. of. Pure and Appl. Sci.)

[1AS-02-Discussion]Discussion

[1AS-02-Conclusion]Conclusion

^○Tomohiro Nobeyama(Fac. of. Pure and Appl. Sci.)

[1AS-03-01]Competitive elimination of tight junction deficient cells regulates epithelial barrier homeostasis

^○Tetsuhisa Otani^1,2, Mikio Furuse^1,2(1.NINS, NIPS, Div. of Cell Structure, 2.Physiol. Sci., SOKENDAI)

[1AS-03-02]Self-organization of polarity for cell migration mediated by an excitable system

^○Satomi Matsuoka^1,2, Masahiro Ueda^1,2(1.Grad. Sch. of Frontier Biosci., Osaka Univ., 2.BDR, RIKEN)

[1AS-03-03_1P-447]Self-organization of periodic circumferential actin cable formation by anisotropic nanocluster fusion in tubulogenesis

^○Sayaka Sekine^1,3, Mitsusuke Tarama^4,2, Tatsuo Shibata², Shigeo Hayashi¹(1.RIKEN BDR, Lab. for Morphogenetic Signaling, 2.RIKEN BDR, Lab. for Physical Biology, 3.Tohoku Univ., Grad. Sch. of Life Sci., 4.Kyushu Univ., Faculty of Sci., Dept. of Physics)

[1AS-03-04_1P-634]Germ cell fate selection by cytoplasmic suction during gametogenesis.

^○Kenji Kimura, Fumio Motegi(Inst. for Genet. Med., Div. of Dev. Phy., Hokkaido Univ.)

[1AS-03-05]Pattern formation of mechano-ERK couplings in cell competition

^○Tsuyoshi Hirashima(Mechanobiology Inst., NUS)

[1AS-03-06]Mechanism of multicellular autonomy through glucose sensing

^○Hiroko Sano¹, Akira Nakamura², Mariko Yamane³, Hitoshi Niwa², Takashi Nishimura⁴, Kimi Araki⁵, Kazumasa Takemoto^2,5, Keiichiro Ishiguro², Hiroki Aoki⁶, Yuzuru Kato⁷(1.Inst. of Life Sci., Kurume Univ., 2.Inst. of Mol. Emb., Kumamoto Univ., 3.Med. Res. Inst., Tokyo Med. and Dent. Univ., 4.Inst. for Mol. and Cell Reg., Gunma Univ., 5.Ctr. for Met. Reg. of Hlthy. Aging, Kumamoto Univ., 6.CV Res. Inst., Kurume Univ., 7.Grad. Sch. of Med., Osaka Univ.)

[1AS-03-07]Left-right symmetry maintenance mechanism of the segmentation clock

^○Kana Ishimatsu¹, Jonathan Touboul¹, Olivier Pourquie²(1.Dept. Math, Brandeis Univ., 2.Dept. Genetics, Harvard Medical School)

[1AS-03-08]Multicellular Autonomy in the Pathogenesis of Cutaneous Mosaic Disorder

^○Akiharu Kubo(Devision of Dermatol., Kobe University Graduate School of Medicine)

[1AS-04-Introduction]Introduction

^○Atsushi Kaneda(Chiba University)

[1AS-04-01]A study of long non-coding RNA regulating cancer cell proliferation

^○Yutaka Kondo(Div. of Cancer Biol., Nagoya Univ. Grad. Sch. of Med.)

[1AS-04-02]Interactive effects of fusion gene and enhancers in sarcomagenesis

^○Miwa Takaka(Cancer Epigenomics Proj, Cancer Inst, JFCR)

[1AS-04-03_1P-119]H3K4 methyltransferase SETD1B regulates H3K4me3 breadth and MYC expression in leukemia

^○Takayuki Hoshii², Shintaro Izumi², Makoto Matsumoto², Rahmutulla Bahityar², Masaki Fukuyo², Kimi Araki³, Scott Armstrong¹, Atsushi Kaneda²(1.Dept. of Ped. Oncol., Dana-Farber Cancer Institute, 2.Dept. of Mol. Oncol., Grad. Sch. of Med., Chiba Univ, 3.Div. of Dev Genet., IRDA., Kumamoto U)

[1AS-04-04]Enhancing CAR-T cell functions through epigenetic modification

^○Yuki Kagoya(Keio University School of Medicine)

[1AS-04-05]Dynamics of biomolecular condensates and cancer biology

^○Hiroshi Suzuki(Div. of Mol. Onco., Nagoya Univ. Grad. Sch. of Med.)

[1AS-04-06_1P-117]A novel transcription mechanism of breast cancer-related genes revealed by deacetylase inhibitions.

^○Hiroaki Tachiwana, Noriko Saitoh(Div., Cancer Biol., JFCR)

[1AS-04-Conclusion]Conclusion

^○Yutaka Kondo(Div. of Cancer Biol., Nagoya Univ. Grad. Sch. of Med.)

[1AS-05-Introduction]Introduction

^○Naoko Hattori(Institute for Advanced Life Sciences, Hoshi University)

[1AS-05-01]Epigenome alterations in the cellular microenvironment and their impact on carcinogenesis

^○Naoko Hattori, Yoshimi Yasukawa, Toshikazu Ushijima(Institute for Advanced Life Sciences, Hoshi University)

[1AS-05-02]Direct Reprogramming of Non-limb Fibroblasts to Cells with Properties of Limb Progenitors

^○Yuji Atsuta(Dept. of Biol., Grad. Sch. of Sci., Kyushu Univ.)

[1AS-05-03_1P-147]Exploring flexible epigenomic information in hepatocytes by predicting multifactorial molecular interactions using chromatin accessibility information

^○Mayumi Oda, Toshiro Sato(Dept. Integrated Med. Biochem., Keio Univ. Sch. of Med.)

[1AS-05-04]Comprehensive functional analysis of the cellular interaction between brain and peripheral immune system involved in tumor progression

^○Yusuke Hamada^1,2, Sara Yoshida¹, Michiko Narita², Naoko Kuzumaki^1,2, Minoru Narita^1,2(1.Dept. Pharmacol., Hoshi Univ., 2.Div. Cancer Pathophysiol., Natl. Cancer Ctr. Res. Inst.)

[1AS-05-05]Mathematical modeling of tumor immunoescape in colorectal cancer

^○Hiroshi Haeno, Koichi Saeki(Inst. Biomed. Sci., Tokyo Univ. of Sci.)

[1AS-05-06_1P-861]Elucidation of intratumoral cellular diversity and the role of ROR1^high tumor-initiating cells in pancreatic cancer.

^○Masaya Yamazaki¹, Shinjiro Hino², Shingo Usuki⁴, Mitsuyoshi Nakao², Takaaki Ito³, Kazuya Yamagata¹(1.Dept. Med. Biochem., Grad. Sch. Med. Sci., Kumamoto Univ., 2.Dept. Med. Cell. Biol., IMEG., Kumamoto Univ, 3.Dept. Med. Technol., Facul. Health Sci., Kumamoto Health Science Univ., 4.LILA., IMEG., Kumamoto Univ.)

[1AS-05-07]Identification of inflammation-associated colon cancer driver genes by Sleeping Beauty transposon mutagenesis

^○Haruna Takeda(Natl. Cancer Ctr.)

[1AS-05-08_1P-578]Generation of the organotypic kidney structure solely from pluripotent stem cells

^○Shunsuke Tanigawa¹, Etsuko Tanaka^2,1, Ryuichi Nishinakamura¹(1.Dept. of Kid. Dev., IMEG., Kumamoto Univ., 2.Dept. of Pediat. Facul. of med., Univ. of Miyazaki)

[1AS-05-Conclusion]Conclusion

^○Haruna Takeda(Natl. Cancer Ctr.)

[1AS-06-01_1P-809]CCN3, a senescence marker of cartilage, correlate with osteoarthritis irrespective of age and weight bearing

Miho Kuwahara², Kazuki Hirose^4,2, Ryuichiro Okuda⁴, Janvier Habumugisha², Sei Kondo², Shanqi Fu², Mitsuaki Ono³, Takayuki Furumatsu⁴, Eiji Nakata⁴, Masaharu Takigawa¹, Satoshi Kubota², ^○Takako Hattori²(1.ARCOCCS. Okayama Univ., Dent. Sch., 2.Dept. of Orthopaedic Surg., Grad. Sch. of Med. Dent. Pharm. Sci., Univ. of Okayama, 3.Dept. of Mol. Biol. Biochem., Grad. Sch. of Med. Dent. Pharm. Sci., Univ. of Okayama, 4.Dept. of Biochem. Mol. Dent., Grad. Sch. of Med. Dent. Pharm. Sci., Univ. of Okayama)

[1AS-06-02]Age dependent changes of epidermal basement membrane and maintaining effect of skin homeostasis by their control

^○Shunsuke Iriyama(SHISEIDO)