Session Details

[1AS-07]【J】Discussing various aspects of neurodegenerative diseases in various "Omics"

Wed. Nov 27, 2024 9:00 AM - 11:15 AM JST
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Room 7(Fukuoka International Congress Center, 4F 413)
Organizer: Satoru Morimoto (Keio University), Yasushi Yabuki (Kumamoto University)
There are various "Omics" approaches to DNA, RNA, and proteins, and many findings have been accumulated through approaches to neurodegenerative disease pathomechanism. Although the objectives of "Omics" vary widely, such as pathological elucidation and biomarker discovery, various "Omics" have succeeded in uncovering previously unseen aspects of neurodegenerative diseases from a broad perspective. In this symposium, researchers who are tackling neurodegenerative diseases using "Omics" will engage in a cross-targeted discussion.

Introduction

[1AS-07-01]RNA phase separation forming scaffold for aggregation of α-synuclein causes synucleinopathy-like neurodegeneration

○Yasushi Yabuki1,2, Kazuya Matsuo1,2, Norifumi Shioda1,2 (1. Dept. Genomic., IMEG., Kumamoto Univ., 2. Grad. Pharm., Kumamoto Univ.)
Comment()

[1AS-07-02]Mechanisms of mRNA-independent translation reaction in mammalian cells

○Shuhei Ebine1,2, Takuya Tomita2, Yasushi Saeki2, Toshifumi Inada1,2 (1. Dept of Biol Sci. Grad. Sch. of Sci, The Univ of Tokyo, 2. IMSUT, The Univ of Tokyo)
Comment()

[1AS-07-03(1P-703)]Anti-Aβ antibody resolves the post-stroke neural reparative function impaired by Aβ pathology

○Kento Otani1,2, Koji Hase2, Takashi Saito3, Takashi Shichita1 (1. Department of Neuroinflammation and Repair, Medical Research Institute, Tokyo Medical and Dental University, 2. Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Keio University., 3. Department of Neurocognitive Science, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University)
Comment()

[1AS-07-04(1P-952)]Exploring Parkinson’s disease related genes using unknomics and transcriptomics

○Suzuki Takayuki1, Bono Hidemasa1 (1. Hiroshima University)
Comment()

[1AS-07-05]Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery

○Satoru Morimoto1 (1. Keio University Regenerative Medicine Research Center)
Comment()

[1AS-07-06]Investigating neuroinflammation in TDP-43 hiPSC-derived microglia

○Kagistia Hana Utami1, Satoru Morimoto1, Hirotaka Watanabe1, Yasue Mitsukura1, Hideyuki Okano1 (1. Keio University)
Comment()

[1AS-07-07]Omics analysis of neurodegenerative diseases using original transcriptome technologies

○Yasuhiro Murakawa1,2 (1. Kyoto University, 2. RIKEN)
Comment()

Conclusion