The 47th Annual Meeting of the Molecular Biology Society of Japan
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Mini-Symposium : [2MS-01] Human-specific mechanisms of brain disorders

[2MS-01]【E】Human-specific mechanisms of brain disorders

Thu. Nov 28, 2024 3:10 PM - 4:30 PM JST
Thu. Nov 28, 2024 6:10 AM - 7:30 AM UTC
Room 1(Fukuoka International Congress Center, 5F 501)
Organizer: Ikuo Suzuki (The University of Tokyo), Yusuke Suenaga (Chiba Cancer Center)
Humans have a larger risk of brain disease including tumors in comparison to non-human hominids. We will introduce recent studies of brain diseases from the evolutionary aspects.
3:10 PM - 3:20 PM JST(6:10 AM - 6:20 AM UTC)

[2MS-01-01]Functional analysis of de novo gene NCYM in the human brain

○Yusuke Suenaga1, Taiki Setoguchi1,2, Kazuma Nakatani1, Harumi Saida1, Daisuke Muto1 (1. Lab. Evo. Oncol. Chiba Cancer Ctr. Res. Ins., 2. Dept. Neurosurg. Chiba Cancer Ctr.)
Comment()
3:20 PM - 3:35 PM JST(6:20 AM - 6:35 AM UTC)

[2MS-01-02]Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

○Sebastiaan van Heesch1,2 (1. Princess Máxima Center for Pediatric Oncology, 2. Oncode Institute)
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3:35 PM - 3:45 PM JST(6:35 AM - 6:45 AM UTC)

[2MS-01-03]Molecular mechanisms underlying the subplate layer expansion in primates during brain evolution

○Chiaki Ohtaka-Maruyama1 (1. Tokyo Metropolitan Institute of Medical Science)
Comment()
3:45 PM - 3:55 PM JST(6:45 AM - 6:55 AM UTC)

[2MS-01-04]Exploring Primate Brain Evolution and Development: A New Horizon in Comparative Neuroscience through a Co-Creation MRI Repository

○Tomoko Sakai1 (1. The National Institute of Science and Technology Policy (NISTEP), Ministry of Education, Culture, Sports, Science and Technology (MEXT))
Comment()
3:55 PM - 4:05 PM JST(6:55 AM - 7:05 AM UTC)

[2MS-01-05(2P-670)]CD63, an exosome-related gene, contributes to the generation of basal neural progenitors to promote cortical expansion

○Boyang An1, Tomonori Kameda2, Fumihiro Morishita1, Mizuki honda1, Kinichi Nakashima2, Takuya Imamura1 (1. Hiroshima Univ., 2. Kyushu Univ.)
Comment()
4:05 PM - 4:20 PM JST(7:05 AM - 7:20 AM UTC)

[2MS-01-06(2P-673)]Spatially Resolved Single-cell Analysis Reveals Human-specific Early Prenatal Specification of Primary Visual Cortex

○Xuyu Qian1,2, Kyle Coleman3, Shunzhou Jiang3, Andrea J Kriz1,2, Jack H Marciano1,2, Chunyu Luo3, Carsen Stringer4, Mingyao Li3, Christopher A Walsh1,2 (1. Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. , 2. Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. , 3. Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA, 4. Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA)
Comment()
4:20 PM - 4:30 PM JST(7:20 AM - 7:30 AM UTC)

[2MS-01-07]Genomic and molecular mechanisms of human brain evolution and diseases

○Ikuo K Suzuki1 (1. The University of Tokyo)
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