The 47th Annual Meeting of the Molecular Biology Society of Japan
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Open-call Symposium : [2AS-13] Understanding the mechanisms of disease and aging through molecular biology

[2AS-13]【E】Understanding the mechanisms of disease and aging through molecular biology

Thu. Nov 28, 2024 9:00 AM - 11:15 AM JST
Thu. Nov 28, 2024 12:00 AM - 2:15 AM UTC
Room 13(Fukuoka International Congress Center, 2F 204)
Organizer: Noriaki Sasai (Nara Institute of Science and Technology), Makoto Ikeya (Kyoto University)
In recent years, a variety of new methods have been developed, including disease model animals, disease recapitulation and generation of organoids using genetically mutant stem cells, long-term culture, and omics technologies, and they have enabled to investigate the causes of diseases and aging at the molecular level. This symposium will focus on studies that use unique approaches to reveal the mechanisms where individuals become diseases and aging conditions, and those proposing methods for prevention, detection, and treatment.
9:00 AM - 9:15 AM JST(12:00 AM - 12:15 AM UTC)

[2AS-13-01]The chromatin modifying factor Polyhomeotic Homolog 1 (Phc1) is required for the brain size determination during embryogenesis

○Noriaki Sasai1, Nur Imaniati Sumantri1, Toshiya Kokaji1, Agnes Ong1, Takuma Shinozuka1, Manabu Shirai2 (1. Nara Institute of Science and Technology, 2. National Cerebral and Cardiovascular Center)
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9:15 AM - 9:30 AM JST(12:15 AM - 12:30 AM UTC)

[2AS-13-02(2P-113)]Loss of “chromatin regions open in random and few cells” in aged gastric stem cells and its potential impact on vulnerability to environmental stimuli

○Yuyu Liu1, Chihiro Takeuchi1, Satoshi Yamashita2, Toshikazu Ushijima1 (1. Dept. of Epigenomics, Inst. of Advanced Life Sci., Hoshi Univ., 2. Dept. of Life Engineering, Facult. of Engineering, Maebashi Inst. of Tech.)
Comment()
9:30 AM - 9:45 AM JST(12:30 AM - 12:45 AM UTC)

[2AS-13-03]Diet and reproductive factors influencing ageing in C. elegans

○Luke Reynoldson1, Rhianne Kelleher1, Hugo Aguilaniu2, Andre Pires da Silva 1 (1. University of Warwick, 2. Serrapilheira)
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9:45 AM - 10:00 AM JST(12:45 AM - 1:00 AM UTC)

[2AS-13-04]Direct neuronal conversion of microglia reinstates neurological function after stroke

○Taito Matsuda1, Takashi Irie1, Kanae Matsuda-Ito1, Nakashima Kinichi1 (1. Kyushu University)
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10:00 AM - 10:15 AM JST(1:00 AM - 1:15 AM UTC)

[2AS-13-05]Pre- and post-natal maturation of lung epithelial cells in interspecies chimeric animals

○Ayako Isotani1, Yamato Murata1, Shun Yuri1, Masahito Ikawa2 (1. NAIST, 2. Osaka Univ.)
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10:15 AM - 10:30 AM JST(1:15 AM - 1:30 AM UTC)

[2AS-13-06]Exploring Early Pathogenesis Mechanism of Fibrodysplasia Ossificans Progressiva Utilizing Patient-derived iPSCs and Mouse Models

○Chengzhu Zhao1, Yoshiko Inada2, Souta Motoike2, Daisuke Kamiya2,3, Kyosuke Hino4, Makoto Ikeya2 (1. Chongqing Medical University, 2. Center for iPS Cell Research and Application (CiRA), Kyoto University, 3. Takeda-CiRA Joint Program, 4. Sumitomo Pharma Co., Ltd)
Comment()
10:30 AM - 10:45 AM JST(1:30 AM - 1:45 AM UTC)

[2AS-13-07]In vivo visualization of p16-expressing cells using p16 reporter mice

○Fumie Nakasuka1, Yasuhiro Yamada1 (1. Univ. Tokyo)
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10:45 AM - 11:00 AM JST(1:45 AM - 2:00 AM UTC)

[2AS-13-08(2P-116)]Functionality of mutant p53 in early tumorigenesis

○Tetsuya Handa1, Eleanor Sheekey1, Ioana Olan1, Masako Narita1, Masashi Narita1 (1. University of Cambridge, CRUK)
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11:00 AM - 11:15 AM JST(2:00 AM - 2:15 AM UTC)

[2AS-13-09]Progenitor Reprogramming: Advancements in Anti-Aging Cell Technologies

○Naoya Takayama1 (1. Chiba University Graduate School of Medicine)
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