Session Details
[2AS-03]【J】Epigenetic regulatory mechanisms in totipotent cells
Thu. Nov 28, 2024 9:00 AM - 11:15 AM JST
Thu. Nov 28, 2024 12:00 AM - 2:15 AM UTC
Thu. Nov 28, 2024 12:00 AM - 2:15 AM UTC
Room 3(Fukuoka International Congress Center, 4F 401+402+403)
Organizer: Hirotsugu Ishizu (Keio University), Mie Kobayashi(Ishihara) (Keio University)
This symposium explores the epigenomic regulatory mechanisms of totipotency in zygotes, crucial for differentiation into various cell types and organism development. We'll discuss the reprogramming process in fertilized eggs and the latest insights into epigenomic networks that define totipotent cells, addressing the challenges in understanding these complex biological processes.
Introduction
[2AS-03-01]Understanding the process of totipotency reprogramming in mouse ES cells
○Hirotsugu Ishizu1, Haruhiko Siomi1 (1. Keio University)
[2AS-03-02]Functional analysis of pioneer transcription factor in totipotent cells
○Wataru Kobayashi1, Kikuë Tachibana1 (1. Max Planck Institute of biochemistry)
[2AS-03-03(2P-609)]Transcriptional reprogramming in the early mouse embryos
○Mizuki Sakamoto1, Aoi Ito1, Sayaka Wakayama2, Hiroyuki Sasaki3, Teruhiko Wakayama2, Takashi Ishiuchi1 (1. Fac. of Life and Environ. Sci., Univ. of Yamanashi, 2. Advanced Biotechnology Center, Univ. of Yamanashi, 3. Div. of Epigenome, MIB, Kyushu Univ.)
[2AS-03-04(2P-101)]Stepwise establishment of facultative heterochromatin by PRC2.2 in early mouse embryos
○Masahiro Matsuwaka1,2, Mami Kumon1, Azusa Inoue1,2 (1. RIKEN IMS, 2. TMU)
[2AS-03-05]Rif1-dependent chromatin structure in mouse ES cells
○Naoko Yoshizawa-Sugata1, Hisao Masai1 (1. Tokyo Metropolitan Institute of Medical Science)
[2AS-03-06]Emergence of replication timing during early mammalian development
○Tsunetoshi Nakatani1, Maria-Elena Torres-Padilla1 (1. Helmholtz Zentrum Munchen)
[2AS-03-07]Endogenous retrovirus-driven regulatory landscapes shape early developmental program in mice
○Akihiko Sakashita1, Chikara Takeuchi2, Toshiya Nakahara1, Shiho Ozawa1, Hirotsugu Ishizu1, Haruhiko Siomi1 (1. Dept. of Mol. Biol., Sch. of Med., Keio Univ., 2. Green Ctr. for Repro. Biol., UT Southwestern)
[2AS-03-08]Understanding the mechanism of PGC specification in rats using pluripotent stem cells
○Mami Oikawa1,3, Masumi Hirabayashi2, Tomoyuki Yamaguchi1, Toshihiro Kobayashi3,2 (1. Tokyo University of Pharmacy and Life Sciences, 2. National Institute for Physiological Sciences, 3. The University of Tokyo)
[2AS-03-09]Single-cell multi-epigenomics analysis of chromatin structure changes associated with changes in cell state
○Akihito Harada1, Takeru Fujii1, Hiroshi Kimura2, Yasuyuki Ohkawa1 (1. Kyuhu Univ., 2. Tokyo Institute of Tech.)