Session Details

[2AS-09]【E】Redefining the conventional view of translation

Thu. Nov 28, 2024 9:00 AM - 11:15 AM JST
Thu. Nov 28, 2024 12:00 AM - 2:15 AM UTC
Room 9(Fukuoka International Congress Center, 3F Main Hall)
Organizer: Hideki Taguchi (Institute of Science Tokyo), Akinobu Matsumoto (Nagoya University)
The common view of translation is transforming drastically. Translation dynamics are highly diverse and flexible, and gene expression regulation at the level of translation contributes much more to cellular processes than expected. Disruption or perturbation of such regulatory systems is associated with human health and disease. This symposium aims to share the current status of translation dynamics with researchers that challenge the conventional view.

Introduction

[2AS-09-01]High-purity synthesis of mRNAs with diverse Cap structures and their biological functions

○Hiroshi Abe1 (1. Nagoya university)
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[2AS-09-02]Structure basis of mitoribosome specific tRNA interaction and the LRPPRC-SLIRP mediated mRNA loading

○Yuzuru Itoh1,2, Vivek Singh2,3, Alexey Amunts2,4 (1. Univ. of Tokyo, 2. Stockholm Univ., 3. Karolinska Institute, 4. Westlake Univ.)
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[2AS-09-03]Risk during translation of acidic-rich amino acid sequences and the impact on proteomes

○Hideki Taguchi1 (1. Science Tokyo, Institute of Integrated Research)
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[2AS-09-04]eIF4G2: More Than Non-Canonical Translation Initiation

○Shinya Yamanaka1,2,3 (1. Center for iPS Cell Research and Application (CiRA), Kyoto University, 2. CiRA Foundation, 3. Gladstone Institute of Cardiovascular Diseases, San Francisco)
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[2AS-09-05]Hidden ORFs and the regulatory mechanisms of their expression

○Akinobu Matsumoto1 (1. Nagoya University)
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[2AS-09-06]Cross-talk between mTORC1, mRNA translation, and energy metabolism in cancer

○Masahiro Morita1,2 (1. University of Texas Health Science Center at San Antonio, 2. Osaka University)
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[2AS-09-07]Molecular mechanism of stress-dependent co-translational degradation on the ER membrane.

○Hisae Kadowaki1 (1. University of Miyazaki)
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[2AS-09-08]Regulation of repeat associated non-AUG translation in repeat expansion disorders.

○Yoshitaka Nagai1,2 (1. Kindai Univ., Faculty Med., 2. Kindai Univ., Life Sci. Res. Inst.)
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General Discussion