The 47th Annual Meeting of the Molecular Biology Society of Japan
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Mini-Symposium : [3MS-10] Mechanism of UV-induced DNA damage revisited by state-of-the-art technologies

[3MS-10]【E】Mechanism of UV-induced DNA damage revisited by state-of-the-art technologies

Fri. Nov 29, 2024 3:10 PM - 4:30 PM JST
Fri. Nov 29, 2024 6:10 AM - 7:30 AM UTC
Room 10(Fukuoka International Congress Center, 2F 201)
Organizer: Syota Matsumoto (The University of Tokyo), Junpei Yamamoto (Osaka University)
Ultraviolet (UV) in sunlight induces chemical alteration of our DNA, and the resultant UV-induced DNA damage blocks our basic activities such as DNA replication and transcription. Organisms have developed various DNA repair mechanisms during evolution to overcome UV-induced DNA damage. In this symposium, we revisit the DNA repair mechanisms from the latest findings revealed by state-of-the-art technologies and open a new gate for future research on UV-induced DNA damage repair mechanism.
3:10 PM - 3:25 PM JST(6:10 AM - 6:25 AM UTC)

[3MS-10-01]Understanding of UV-damaged DNA repair mechanism in chromatin by cryo-electron microscopy

○Syota Matsumoto1, Yoshimasa Takizawa1, Mitsuo Ogasawara1, Kana Hashimoto1, Junpei Yamamoto2, Shigenori Iwai2, Kaoru Sugasawa3, Hitoshi Kurumizaka1 (1. IQB, The Univ. of Tokyo, 2. Grad. Sch. of Eng. Sci, Osaka Univ., 3. Biosignal Res. Cent, Kobe Univ.)
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3:25 PM - 3:45 PM JST(6:25 AM - 6:45 AM UTC)

[3MS-10-02]Single-molecule imaging reveals UV-damage search mechanisms of UV-DDB and XPC-RAD23B in nucleotide excision repair

Soyeong An1, Na Young Cheon1, Masayuki Kusakabe2, Hyun-Suk Kim3, Hidetsugu Kozono3, Kaoru Sugasawa, Orlando D Scharer3,4,1, ○JA YIL LEE1 (1. Ulsan National Institute of Science and Technology, Republic of Korea, 2. Biosignal Research Center, Kobe University, Kobe, Hyogo 657-8501, Japan, 3. Institute of Basic Science Center for Genomic Integrity, Ulsan, 44919, Republic of Korea, 4. Graduate School of Health Science and Technology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea)
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3:45 PM - 4:00 PM JST(6:45 AM - 7:00 AM UTC)

[3MS-10-03]Live cell imaging-based analysis for DNA damage response

○Arato Takedachi1, Gakuto Fukushima2, Yoshihiro Fujimura2, Ayano Baba1, Kousuke Matsuo2, Rui Oda1, Hayato Nishino1, Haruto Kojima2, Isao Kuraoka2 (1. Fukuoka University, 2. Graduate School of Science, Fukuoka University)
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4:00 PM - 4:15 PM JST(7:00 AM - 7:15 AM UTC)

[3MS-10-04]Loss and gain of chloroplast localization of CPD photolyase during plant evolution

○Momo Otake1, Takahiro Nii1, Mika Teranishi1, Kaoru Yoshiyama (Okamoto)1, Jun Hidema1 (1. Grad. Life Sci., Tohoku Univ.)
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4:15 PM - 4:30 PM JST(7:15 AM - 7:30 AM UTC)

[3MS-10-05]Transcription-coupled repair of photolesions -mechanisms of action, regulation, and associated human disorders

○Tomoo Ogi1 (1. Nagoya University)
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