The 47th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Open-call Symposium : [3PS-10] The essence of genome replication fidelity - from initiation to termination

[3PS-10]【E】The essence of genome replication fidelity - from initiation to termination

Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 10(Fukuoka International Congress Center, 2F 201)
Organizer: Yasukazu Daigaku (Japanese Foundation for Cancer Research), Tatsuro Takahashi (Kyushu University)
DNA replication has been a long-standing focus in molecular biology and is intimately linked to transcription, recombination, repair and chromosome organization. By examining the coordination of events from the initiation to the termination of replication, this symposium aims to shed light on how the interactions between replication and genome maintenance pathways can impact the accuracy of replication and overall genomic stability.
4:45 PM - 4:46 PM JST(7:45 AM - 7:46 AM UTC)

Introduction

4:46 PM - 5:02 PM JST(7:46 AM - 8:02 AM UTC)

[3PS-10-01]CDK-dependent regulation of DONSON function in DNA replication initiation

○Yoshitami Hashimoto1 (1. Tokyo University of Pharmacy and Life Sciences)
Comment()
5:02 PM - 5:18 PM JST(8:02 AM - 8:18 AM UTC)

[3PS-10-02]The mechanism defining replication initiation zones in human cells

Xiaoxuan Zhu1, Atabek Bektash1,3, Yuki Hatoyama1,3, Sachiko Sakamoto1, Yasukazu Daigaku2, ○Masato Kanemaki1,3,4 (1. National Institute of Genetics, 2. Cancer Institute of Japanese Foundation for Cancer Research, 3. Graduate Institute for Advanced Studies, SOKENDAI, 4. Department of Biological Science, The University of Tokyo)
Comment()
5:18 PM - 5:34 PM JST(8:18 AM - 8:34 AM UTC)

[3PS-10-03]Targeted resolution of R-loops by TUG1 and RNA Helicases

○Miho M Suzuki1, JIngqi Xie1, Kenta Iijima1, Keiko Shinjo1, Yutaka Kondo1 (1. Dept. of Oncology., Grad. Sch. of Med., Nagoya Univ.)
Comment()
5:34 PM - 5:49 PM JST(8:34 AM - 8:49 AM UTC)

[3PS-10-04(3P-064)]Smarcad1 and MutSα catalyze unidirectional sliding of a nucleosome away from a mismatch to facilitate mismatch repair on chromatin

○Eiichiro Kanatsu1, Riki Terui2, Tamiko Minamisawa3, Yasukazu Daigaku3, Tatsuro Takahashi2 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Faculty of Science, Kyushu University, 3. Cancer Institute, Japanese Foundation for Cancer Research)
Comment()
5:49 PM - 6:01 PM JST(8:49 AM - 9:01 AM UTC)

[3PS-10-05(3P-075)]Biochemical and structural analyses of the DNA damage recognition by XPF-ERCC1 in the nucleosome

○Aya Yoshida1,2, Syota Matsumoto1, Yoshimasa Takizawa1, Mitsuo Ogasawara1, Isao Kuraoka3, Hitoshi Kurumizaka1,2 (1. IQB, The Univ. of Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., The Univ. of Tokyo, 3. Dept. of Chem., Grad. Sch. of Sci., Fukuoka Univ.)
Comment()
6:01 PM - 6:17 PM JST(9:01 AM - 9:17 AM UTC)

[3PS-10-06]Functional analysis of ubiquitin ligase RFWD3 in DNA replication of damaged DNA in human cells

○Rie Kanao1,2, Yuji Masuda1,2, Chikahide Masutani1,2 (1. Res. Inst. Environ. Med., Nagoya Univ., 2. Nagoya Univ. Grad. Sch. Med.)
Comment()
6:17 PM - 6:32 PM JST(9:17 AM - 9:32 AM UTC)

[3PS-10-07]A genome-wide investigation into the roles of error-prone DNA polymerases in human DNA replication

○Lewis John Bainbridge1, Yuji Masuda2, Mami Takahashi1, Tamiko Minamisawa1, Chikahide Masutani2, Yasukazu Daigaku1 (1. Japanese Foundation for Cancer Research, 2. Nagoya Univ.)
Comment()
6:32 PM - 6:44 PM JST(9:32 AM - 9:44 AM UTC)

[3PS-10-08(3P-083)]Human AAA+ ATPase FIGNL1 facilitates post-replicative disassembly of RAD51 to suppress RAD51-mediated ultra-fine bridge formation

○Kenichiro Matsuzaki1, Miki Shinohara1,2 (1. Grad. Sch. Agri., Kindai Univ., 2. ATIRI, Kindai Univ.)
Comment()
6:44 PM - 7:00 PM JST(9:44 AM - 10:00 AM UTC)

[3PS-10-09]How to terminate DNA replication during early mitosis

○Ryo Fujisawa1, Karim Labib1 (1. University of Dundee)
Comment()
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