Session Details

[3AS-03]【J】Retroelements: Friends or Foes?

Fri. Nov 29, 2024 9:00 AM - 11:15 AM JST
Fri. Nov 29, 2024 12:00 AM - 2:15 AM UTC
Room 3(Fukuoka International Congress Center, 4F 401+402+403)
Organizer: So Nakagawa (Tokai University), Hirosuke Shiura (University of Yamanashi)
Retroelements (REs) are retrotranscribed from RNA to DNA and inserted into genomes, some of which are derived from LINEs and viruses. REs occupy a large portion of the genomes of various organisms. These are usually repressed by epigenetic mechanisms and have been considered as "junk" or even "garbage". However, recent studies have revealed that REs act as "foes" involved in various diseases, and at the same time, they also function as "friends" that play important roles in the development and physiological functions. In this symposium, we would like to report and discuss various aspects of REs.

Introduction

[3AS-03-01]Endogenous retroviruses provide protection against HSV-2 disease.

Tianyang Mao2, Radeesha Jayewickreme2, William Philbrick2, Rebecca S Treger2, Peiwen Lu2, Huiping Dong2, Grace Bodykevich1, Kaila Villarey1, May Dang-Lawson1, W. Austin Guild1, Tatiana J Lau1, Akiko Iwasaki2, ○Maria Tokuyama1 (1. The University of British Columbia, 2. Yale University School of Medicine)
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[3AS-03-02]The role of endogenous retroviruses in mouse-specific placenta development

○Toshiya Nakahara1, Fiona Quirion1, Akihiko Sakashita1, Haruhiko Siomi1 (1. Dept. of Mol. Biol., Sch. of Med., Keio Univ.)
Comment()

[3AS-03-03]Diversity of retroelement-derived genes

○Koichi Kitao1 (1. Nagoya Univ.)
Comment()

[3AS-03-04(3P-922)]Retrotransposon insertion in the FGFR1 gene is responsible for congenital hypogonadotropic hypogonadism

○Yoko Kuroki1,2,3, Kentaro Sawano4, Erina Suzuki5, Yasuko Ogiwara5, Keisuke Nagasaki4, Maki Fukami3,5 (1. Dept. of Genome medicine, National Center for Child Health and Development, 2. Div. of Collaborative Research, National Center for Child Health and Development, 3. Div. of Diversity Research, National Center for Child Health and Development, 4. Div. of Pediatrics, Dept. of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, 5. Dept. of Molecular Endocrinology, National Center for Child Health and Development)
Comment()

[3AS-03-05(3P-144)]Genome-wide N-terminally truncated novel protein isoform production triggered by springer, an RE escaped from piRNA system

○Mai Moritoh1, Toru Morita2, Chikara Takeuchi3, Yuka W. Iwasaki3, Mikiko C. Siomi1 (1. The University of Tokyo, 2. Sch. of Med., Yokohama City Univ., 3. IMS, RIKEN)
Comment()

[3AS-03-06]How plants identify transposons and genes - Contribution of histone H2A variants to epigenomic pattern formation -

Shoko Oda1,2, Tetsuji Kakutani2, ○Taiko Kim To1,2 (1. Institute of Science Tokyo, 2. The University of Tokyo)
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[3AS-03-07]Evolution by Gene Acquisition: What have retroviruses done to mammals?

○Fumitoshi Ishino1, Tomoko Kaneko-Ishino2 (1. Tokyo Medical and Dental University, 2. Sch of Med, Tokai University)
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