The 47th Annual Meeting of the Molecular Biology Society of Japan
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Open-call Symposium : [3PS-03] Higher-Order Molecular Clusters: Emerging Frontiers in Genome Dynamics Research

[3PS-03]【E】Higher-Order Molecular Clusters: Emerging Frontiers in Genome Dynamics Research

Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 3(Fukuoka International Congress Center, 4F 401+402+403)
Organizer: Motoko Takahashi (Japanese Foundation for Cancer Research), Masatoshi Hara (Osaka University)
Genome dynamics, including DNA transcription, replication, repair, and segregation, are the fundamentals of living systems. The recent advances in super-resolution imaging, electron microscopies, protein manipulation techniques, and computational biology have revealed higher-order molecular complex structures and their unique functions to control genome dynamics. This symposium aims to shed light on such molecular clusters and discuss future perspectives in the field.
4:45 PM - 4:47 PM JST(7:45 AM - 7:47 AM UTC)

Introduction

4:47 PM - 5:05 PM JST(7:47 AM - 8:05 AM UTC)

[3PS-03-01]Regulatory loop for Aurora B localization mediated through CENP-C ensures accurate chromosome segregation

○Masatoshi Hara1, Weixia Kong1, Yurika Tokunaga2, Kazuhiro Okumura2, Yasuhiro Hirano1,3, Jiahang Miao1, Yusuke Takenoshita1, Masakazu Hashimoto1,4, Hiroshi Sasaki1, Toshihiko Fujimori5,6, Yuichi Wakabayashi2, Tatsuo Fukagawa1 (1. FBS, Osaka Univ., 2. Research Inst., Chiba Cancer Center , 3. Cancer Inst., JFCR, 4. Sch. Med., Fukushima Med. Univ., 5. Dev. Embryology, NIBB, 6. SOKENDAI)
Comment()
5:05 PM - 5:24 PM JST(8:05 AM - 8:24 AM UTC)

[3PS-03-02(3P-435)]A synthetic microscale kinetochore establishes a biorientation-like state

○Kohei Asai1, Yuanzhuo Zhou1, Osamu Takenouchi1, Tomoya Kitajima1,2 (1. RIKEN Center for Biosystems Dynamics Research , 2. Graduate School of Biostudies, Kyoto university)
Comment()
5:24 PM - 5:43 PM JST(8:24 AM - 8:43 AM UTC)

[3PS-03-03]Mitotic Stress-dependent activation of the tumor suppressor p53

Hazrat Belal1, Esther Feng Ying Ng1, ○Franz Meitinger Meitinger1 (1. Okinawa Institute of Science and Technology)
Comment()
5:43 PM - 6:02 PM JST(8:43 AM - 9:02 AM UTC)

[3PS-03-04]Dynamic transcription factor clustering acts as a hub for enhancer mediated ultra long-range genomic interactions.

○Koji Kawasaki1, Takashi Fukaya1,2 (1. Institute for Quantitative Biosciences, The University of Tokyo, 2. Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo)
Comment()
6:02 PM - 6:21 PM JST(9:02 AM - 9:21 AM UTC)

[3PS-03-05(3P-361)]iChIP, a screen method to isolate protein complexes on a specific promoter in planta, identified novel transcriptional regulators of hormone biosynthesis under environmental stress conditions

○Hikaru Sato1,2, Satoru Fujimoto3, Miki Fujita2, Fuminori Takahashi2, Keiko Kuwata4, Sachihiro Matsunaga1,3, Kazuko Yamaguchi-Shinozaki5,6, Kazuo Shinozaki2 (1. Dept. of Integr. Biosci., Univ. Tokyo, 2. RIKEN CSRS, 3. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci., 4. ITbM, Nagoya Univ., 5. Grad. Sch. Agr. Life Sci., Univ. Tokyo, 6. Res. Inst. Agr. Life Sci., Tokyo Univ. Agr.)
Comment()
6:21 PM - 6:40 PM JST(9:21 AM - 9:40 AM UTC)

[3PS-03-06]Physicochemical understanding of nuclear phase separation using ATPS droplets

○Miho Yanagisawa1 (1. Univ. Tokyo, KIS)
Comment()
6:40 PM - 6:58 PM JST(9:40 AM - 9:58 AM UTC)

[3PS-03-07]How molecular clustering can drive mitotic chromosome assembly in mitosis

○Motoko Takahashi1, Chang Liu1, Toru Hirota1 (1. Div. of Experimental Pathol, The Cancer Institute, Japanese Foundation for Cancer Research)
Comment()
6:58 PM - 7:00 PM JST(9:58 AM - 10:00 AM UTC)

Conclusion

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