Session Details
[3MS-07]【J】Toward a Metabolic Renaissance: gazing at the nature by perturbing “homeostasis"
Fri. Nov 29, 2024 3:10 PM - 4:30 PM JST
Fri. Nov 29, 2024 6:10 AM - 7:30 AM UTC
Fri. Nov 29, 2024 6:10 AM - 7:30 AM UTC
Room 7(Fukuoka International Congress Center, 4F 413)
Organizer: Soshiro Kashio (The University of Tokyo), Keigo Morita (The University of Tokyo)
Due to the fundamentality of metabolism for life, it has been regarded as a commonsense that our body and cells respond to perturbations for keeping metabolic homeostasis. On the other hand, metabolic research is a classical but revived research field thanks to the development of measurement techniques, analytical methods, and research targets. In this symposium, we will try to reexamine the common sense of metabolic homeostasis. This symposium will attempt to "rediscover" metabolic research by seeking new approaches from the viewpoints of phenomena, elements, measurements, and systems.
[3MS-07-01]Consumption and localization control mechanisms underlying stabilization of SAM metabolism
○Soshiro Kashio1, Masayuki Miura1 (1. Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo)
[3MS-07-02(3P-781)]A gut ceramidase activity determines the species- and strain-specific aging speed
○Ayami Takaochi1, Kota Abe1, Tohru Ishitani1 (1. Osaka university, RIMD)
[3MS-07-03]Global stoichiometry conservation hierarchy in cells and simultaneous realization of adaptability and homeostasis of cells — from Raman-omics correspondence to an architectural principle of cells —
○Ken-ichiro F. Kamei1, Koseki J. Kobayashi-Kirschvink2,3, Takashi Nozoe1,4,5, Hidenori Nakaoka6, Miki Umetani1,4,5, Yuichi Wakamoto1,4,5 (1. Graduate School of Arts and Sciences, The University of Tokyo, 2. Broad Institute of MIT and Harvard, 3. G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, 4. Research Center for Complex Systems Biology, The University of Tokyo, 5. Universal Biology Institute, The University of Tokyo, 6. Advanced Research Promotion Center, Tokushima University)
[3MS-07-04]Omics approach to lipid metabolic changes for mammalian hibernation
○Akari Yamauchi1,2, Junpei Yamashita1, Yuki Sugiura3, Yuta Matsuoka3, Yoshifumi Yamaguchi1,2 (1. Hibernation metabolism, physiology, and development Group, Inst. Low Temp. Sci., Hokkaido Univ. , 2. Biosphere Science, Grad. Sch. Env. Sci., Hokkaido Univ., 3. Grad. Sch. Med., Kyoto Univ.)
[3MS-07-05]Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in liver of healthy and obese mice
○Keigo Morita1,2, Atsushi Hatano1,3,4, Toshiya Kokaji1,5, Hikaru Sugimoto6, Tsuchiya Takaho7,8, Haruka Ozaki7,8, Riku Egami9, Dongzi Li1, Akira Terakawa1, Satoshi Ohno1,2,10, Hiroshi Inoue11, Yuka Inaba11, Yutaka Suzuki9, Masaki Matsumoto3, Masatomo Takahashi12, Yoshihiro Izumi12, Takeshi Bamba12, Akiyoshi Hirayama13, Tomoyoshi Soga13, Shinya Kuroda1,2,6,9 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. Molecular Genetics Research Laboratory, Graduate School of Science, The University of Tokyo, 3. Graduate School of Medical and Dental Sciences, Niigata University, 4. Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, 5. Data Science Center, Nara Institute of Science and Technology, 6. Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 7. Bioinformatics Laboratory, Institute of Medicine, University of Tsukuba,, 8. Center for Artificial Intelligence Research, University of Tsukuba, 9. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 10. Department of AI Systems Medicine, M&D Data Science Center, Tokyo Medical and Dental University, 11. Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, 12. Division of Metabolomics, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 13. Institute for Advanced Biosciences, Keio University)