The 47th Annual Meeting of the Molecular Biology Society of Japan
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Open-call Symposium : [3AS-08] Understanding cell-type-specific metabolic changes toward regulation of systemic metabolism in life-style related diseases

[3AS-08]【E】Understanding cell-type-specific metabolic changes toward regulation of systemic metabolism in life-style related diseases

Fri. Nov 29, 2024 9:00 AM - 11:15 AM JST
Fri. Nov 29, 2024 12:00 AM - 2:15 AM UTC
Room 8(Fukuoka International Congress Center, 4F 414)
Organizer: Yuta Hiraike (The University of Tokyo), Chitoku Toda (Kumamoto University)
Genes involved in oxidative phosphorylation are coordinately down-regulated in skeletal myocytes and adipocytes in subjects with diabetes. Similarly, mechanistic links between cell-type-specific metabolic changes in neurons, hepatocytes, macrophages and life-style related diseases has been investigated. In this symposium, young researchers will join to share their insights on cell-type-specific metabolic changes toward regulation of systemic metabolism.
9:00 AM - 9:04 AM JST(12:00 AM - 12:04 AM UTC)

Introduction

9:04 AM - 9:26 AM JST(12:04 AM - 12:26 AM UTC)

[3AS-08-01]A multi-omics approach to identify genes important for the regulation of anti-diabetic and anti-inflammatory lipids

○Anna Santoro1, Zhenlong Chen1, Mark P. Keller2, Hazel Shan3, Andrew T. Nelson4, Alan D. Attie2, Dionicio Siegel4, Alan Saghatelian 5, Barbara B. Kahn1 (1. Beth Israel Deaconess Medical Center, Harvard Medical School, 2. Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA, 3. Clayton Foundation Peptide Biology Laboratories, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, United States, 4. Division of Pharmaceutical Chemistry, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093., 5. The Salk Institute for Biological Studies, 10010 N. Torey Pines Rd, La Jolla, CA, 92037-1002, USA)
Comment()
9:26 AM - 9:42 AM JST(12:26 AM - 12:42 AM UTC)

[3AS-08-02(3P-887)]A novel signaling pathway of brown adipocyte activation

○Masaji Sakaguchi1, Shota Okagawa1, Yuma Okubo1, Yuri Takekuma1, Eiichi Araki1, Naoto Kubota1 (1. Faculty of Life Sciences, Kumamoto University)
Comment()
9:42 AM - 9:55 AM JST(12:42 AM - 12:55 AM UTC)

[3AS-08-03]Reciprocal regulation of thermogenesis and inflammation in brown adipocytes by NFIA

○Yuta Hiraike1 (1. The University of Tokyo)
Comment()
9:55 AM - 10:11 AM JST(12:55 AM - 1:11 AM UTC)

[3AS-08-04]Investigation of the role of mitochondrial dynamics in the understanding of the pathogenesis of MASH.

○Yukina Takeichi1 (1. Kyushu University Hospital Department of Endocrine, Metabolism and Deiabetes/Department of Medicine and Bioregulatory Science)
Comment()
10:11 AM - 10:27 AM JST(1:11 AM - 1:27 AM UTC)

[3AS-08-05]Intracellular metabolic alterations in dying cells and chronic inflammation

○Miyako Tanaka1, Takayoshi Suganami1 (1. Nagoya University)
Comment()
10:27 AM - 10:43 AM JST(1:27 AM - 1:43 AM UTC)

[3AS-08-06(3P-892)]Deciphering the Dynamics and Functions of Metabolic Networks from Their Network Structures

○TAKASHI OKADA1, Mochizuki Atsushi1, Huang YongJin1 (1. Kyoto University)
Comment()
10:43 AM - 10:59 AM JST(1:43 AM - 1:59 AM UTC)

[3AS-08-07(3P-900)]Mechanism of age-dependent decline in brown adipose tissue thermogenesis leading to middle-aged obesity

○Manami Oya1, Kazuhiro Nakamura1 (1. Nagoya Univ.)
Comment()
10:59 AM - 11:15 AM JST(1:59 AM - 2:15 AM UTC)

[3AS-08-08]Role of prostaglandins in hypothalamic glucose-sensing

○Chitoku Toda1 (1. Department of Neuroscience for Metabolic Control, Faculty of Life Sciences,Kumamoto University)
Comment()
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