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Dynamic regulation of H3K9 di-methylation drives mouse minor zygotic genome activation

Chromatin plays a key role in the regulation of gene expression. However, it is unclear how gene expression during development and differentiation is regulated through chromatin structure to determine the cell fate. A higher-order chromatin structure organized by multiple regulatory layers in specific cell types can be an acquired code, or “epicode”. We are aiming to reveal how epicode is established and defines the cell fate.

【E】Deciphering the epicode of chromatin controling cell fate decisions

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[2AS-02-01]Dynamic regulation of H3K9 di-methylation drives mouse minor zygotic genome activation

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