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Wed. Dec 3, 2025

Thu. Dec 4, 2025

Fri. Dec 5, 2025

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Elucidation of the mechanism of nuclear structure formation through LLPS of CTCF

Transposable elements (TEs) including SINEs and LINEs occupy a large part of the mammalian genome showing distinct distribution patterns. SINE-mediated recruitment of CTCF and LINE-mediated liquid-liquid phase separation may synergistically promote 3D genome organization. In this workshop, we will introduce the latest research on the relationships between TEs and the 3D genome structure. The core concept that TE distribution constitutes a “TE code" to regulate the higher-order nuclear organization will be discussed.

【J】Higher order genome regulation and function mediated by the transposable element code

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[3AS-15-02]Elucidation of the mechanism of nuclear structure formation through LLPS of CTCF

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