Session Details
[1PS-02]【E】Frontier Research on mechanisms underlying the evolution of human brain
Wed. Dec 3, 2025 2:20 PM - 4:20 PM JST
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Room 2(Pacifico Yokohama Conference Center 3F, 301)
Organizer: Ikuo Suzuki (The University of Tokyo), Ryohei Iwata (VIB-KU Leuven)
Humans have evolved outstanding cognitive abilities by enlarging and complexifying their cerebral cortex. In this symposium, we will invite leading scientists who utilize state-of-the-art technologies in the field to approach human brain evolution. Through sharing recent findings and discussing with international experts, we aim to enhance our understanding of the molecular and cellular mechanisms that drive human brain evolution.
[1PS-02-01]Mitochondrial fatty acid oxidation sets the species-specific timescale of temporal patterning in the developing cerebral cortex
○Ryohei Iwata1 (1. VIB-KU Leuven)
[1PS-02-02]Uncovering Intrinsic Regulators of Human Neuronal Maturation via Transcriptomic Profiling and CRISPR-Based Functional Screens
○Leila Boubakar1, Ryohei Iwata1, Emir Erkol1, Pierre Vanderhaeghen1 (1. VIB-KU Leuven – Center for Brain and Disease Research)
[1PS-02-03]Integrated ERK/PKA-YAP/TAZ-SHH signaling drives cortical evolutionary expansion and lineage diversification
○Zhengang YANG1 (1. Institutes of Brain Science, Fudan University, Shanghai, China)
[1PS-02-04]The role of cerebrospinal fluid in coordinating neural stem cell proliferation and cortical expansion
○Jun Hatakeyama1, Mami Akaike2, Haruka Sato1, Saya Okada1, Yuta Nakashima2, Kenji Shimamura1 (1. IMEG Kumamoto Univ., 2. FAST Kumamoto Univ.)
[1PS-02-05]Magnitude Matters: Upregulated Gene Expression as a Driver of Human Brain Evolution
○Ikuo K. Suzuki1, Xuanhao D. Zhou1 (1. The University of Tokyo)