The 48th Annual Meeting of the Molecular Biology Society of Japan

Chairperson：TBD (Nikon Solutions Co.,Ltd.)

TBD

Conventional microscopy techniques face limitations in spatial and temporal resolution as well as signal intensity, making it difficult to clearly capture fleeting events inside cells. In this seminar, I will introduce “cryo-optical microscopy,” a method that allows cells to be rapidly frozen within a very short time during observation, preserving their instantaneous state for high-resolution and high-sensitivity imaging. This approach enables visualization of transient cellular behaviors while maintaining molecular distributions and states and further offers the advantages of reducing photodamage and detecting weak signals. Cryo-optical microscopy provides a new approach for studying cellular dynamics and molecular biology.