The 48th Annual Meeting of the Molecular Biology Society of Japan
Advanced Search

Session Details

Mini-Symposia

[3MS-17]【E】De novo gene birth as a molecular origin of evolutionary innovation and biodiversity

Fri. Dec 5, 2025 11:15 AM - 12:35 PM JST
Fri. Dec 5, 2025 2:15 AM - 3:35 AM UTC
Room 17(Pacifico Yokohama Conference Center 5F, 503)
Organizer: Yusuke Suenaga (Chiba Cancer Center Research Institute), Zhao Li (The Rockefeller University)
De novo genes are newly evolved genes emerged from noncoding genomic regions during evolution. They have been identified in a wide range of species, from yeast to humans, and contribute to the creation of species characteristics. Because of their short lifespan, the birth and loss of de novo genes generates genetic diversity within a lineage.This mini-symposium will bring together researchers from evolutionary biology, structural biology, and medicine to present their latest findings on de novo genes.
11:15 AM - 11:18 AM JST(2:15 AM - 2:18 AM UTC)

Introduction

11:18 AM - 11:33 AM JST(2:18 AM - 2:33 AM UTC)

[3MS-17-01]How new genes and new proteins are born

Junhui Peng1, Nicolas Svetec1, ○Li Zhao1 (1. The Rockefeller University)
Comment()
11:33 AM - 11:38 AM JST(2:33 AM - 2:38 AM UTC)

Q & A for Each Presentation

11:38 AM - 11:53 AM JST(2:38 AM - 2:53 AM UTC)

[3MS-17-02]The gene regulatory networks and transcription factors controlling the expression of de novo originated genes.

○Nicolas Svetec1, Junhui Peng1, Bing-Jun Wang1, Li Zhao1 (1. The Rockefeller University)
Comment()
11:53 AM - 11:58 AM JST(2:53 AM - 2:58 AM UTC)

Q & A for Each Presentation

11:58 AM - 12:10 PM JST(2:58 AM - 3:10 AM UTC)

[3MS-17-03]Human de novo gene NCYM regulates human-specific mitotic mechanisms in neuroblastoma

○Ummi Maryam Zulfin1,2, Kazuma Nakatani1, Daisuke Muto1,2, Seigi Yamamoto1, Hiroyuki Kogashi1, Kazuto Kugou3, Osamu Shimozato4, Rohmad Yudi Utomo6, Edy Meiyanto6, Yoshitaka Hippo5, Yusuke Suenaga1 (1. Laboratory of Evolutionary Oncology, Chiba Cancer Center Research Institute, Chiba, Japan, 2. Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan, 3. Department of Applied Genomics, Kazusa DNA Research Institute, Japan, 4. Laboratory of Oncogenomics, Chiba Cancer Center Research Institute, Chiba, Japan, 5. Laboratory of Precision Tumor Model Systems, Chiba Cancer Center Research Institute, Chiba, Japan, 6. Cancer Chemoprevention Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Indonesia)
Comment()
12:10 PM - 12:15 PM JST(3:10 AM - 3:15 AM UTC)

Q & A for Each Presentation

12:15 PM - 12:30 PM JST(3:15 AM - 3:30 AM UTC)

[3MS-17-04]Solution structure of oncogenic de novo protein NCYM studied by synchrotron radiation

○Tatsuhito Matsuo1 (1. Hiroshima International University)
Comment()
12:30 PM - 12:35 PM JST(3:30 AM - 3:35 AM UTC)

Q & A for Each Presentation

Back to Category List