MMIJ 2015,Matsuyama
Sep 8 - Sep 10, 2015Ehime University
MMIJ 2015,Matsuyama
Sep 8 - Sep 10, 2015Ehime University
[1202]Sewage recycling of heavy metal polluted water with the use of genetically modified cyanobacteria
○森田勇人1, Shelake Rahul Mahadev2, 林秀則2(1.愛媛大学農学部, 2.愛媛大学無細胞生命工学研究センター)
司会:駒井武(東北大学)
Metal-responsive transcriptional regulations are the key features in heavy metal ion tolerance for prokaryotes.In freshwater cyanobacterium /Synechococcus/ sp. PCC 7942, /smt/ locus consists of two
divergently transcribed genes, /smtA/.( metallothionein) and /smtB/ (repressor of /smtA/transcription).
The molecular mechanism of transcription regulation and metal ion sensing with SmtB and the protein engineering techniques to improve the Zn^2+ binding ability in SmtA are studied with physicochemical techniques. We will show the results and applications of these studies.
divergently transcribed genes, /smtA/.( metallothionein) and /smtB/ (repressor of /smtA/transcription).
The molecular mechanism of transcription regulation and metal ion sensing with SmtB and the protein engineering techniques to improve the Zn^2+ binding ability in SmtA are studied with physicochemical techniques. We will show the results and applications of these studies.