Presentation Information
[1LBA-053]SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-dysregulated dopamine transmission and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice
*Jun Zhu1, Sarah E Davis1, Matthew J Strauss1, Ana Jimenez Torres1, Mark Ferris4, Chang-Guo Zhan2, Jay P McLauphlin3, Sam Ananthan5, Corinne E Augelli-Szafran5 (1. College of Pharmacy, University of South Carolina, Columbia, SC, USA, 2. College of Pharmacy, University of Kentucky, Lexington, KY, USA, 3. College of Pharmacy, University of Florida, Gainesville, FL, USA, 4. School of Medicine, Wake Forest University, Winston-Salem, NC, USA, 5. Department of Chemistry, Southern Research Institute, Birmingham, AL. USA)
Keywords:
dopamine,HIV-1 Tat,transporter,cocaine
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