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Complementary roles of the hippocampus and the entorhinal cortices for reward learning and consolidation during sleep

For the past several decades, it has been controversial whether the entorhinal-hippocampal memory circuit receives reward signals similar to those received in the striatum. Recently, it becomes clearer that place cells in the hippocampus represent reward information (Kaufman et al., Neuron 2020), grid cells in the medial entorhinal cortex represent reward signals (Boccara et al., Science 2019; Buttler et al., Science 2019), and the lateral entorhinal cortex receives reward signals from the ventral tegmental area (Lee et al., Nature, 2021). In this symposium, we will discuss roles of the reward signals in the entorhinal-hippocampal memory circuit.

NEURO2022

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[1S09e-02]Complementary roles of the hippocampus and the entorhinal cortices for reward learning and consolidation during sleep

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