Session Details
[2P]B. Development, Regeneration and Plasticity
Fri. Jul 1, 2022 11:00 AM - 12:00 PM JST
Fri. Jul 1, 2022 2:00 AM - 3:00 AM UTC
Fri. Jul 1, 2022 2:00 AM - 3:00 AM UTC
Poster Session Hall 2 Ginowan City Gymnasium
[2P-105]CEP152-deficiency promotes impaired centrosome duplication- and cell death-dependent dwarfism in mice
*Nanako Hamada1, Takuma Nishijo1, Masashi Nishikawa1, Tomoko Uehara2, Toshiki Takenouchi2, Kenjiro Kosaki2, Seiji Mizuno3, Koh-ichi Nagata1 (1. Aichi Developmental Disability Center, Institute for Developmental Research, 2. Center for medical genetics, Dept Med, Keio Univ, 3. Aichi Developmental Disability Center, Central Hospital)
[2P-106]Evolution of an mRNA transport mechanism in radial glial cells by acquisition of a unique zip code sequence in placental mammals
*Takako Kikkawa1, Yoshio Wakamatsu1, Yukiko U. Inoue2, Kunihiro Suzuki3, Takayoshi Inoue2, Noriko Osumi1 (1. Dept Dev Neurosci, Grad Sch Med, Tohoku Univ, 2. Dept Biochem Cell Biol, NCNP, 3. Res Inst Oral Sci, Nihon Univ, Sch Dent Matsudo )
[2P-107]Drp1 SUMOylation regulates cortical development via mitochondrial dynamics
*Seiya Yamada1, Ayaka Sato1, Naotada Ishihara2, Hiroki Akiyama3, Shin-ichi Sakakibara1 (1. Lab Mol Neuro Bio, Grad Sch Hum Sci, Waseda Univ, 2. Dep Biol Sci, Grad Sch Sci, Osaka Univ, 3. Adv Res Cent Hum Sci, Waseda Univ)
[2P-108]Dynamics of Subplate neurons in postnatal development
*Keiko Moriya-Ito1, Yusuke Sugita1,2, Yoshiko Takahashi1, Chiaki Ohtaka-Maruyama1 (1. Tokyo Met Ins of Med Sci, Tokyo, Japan, 2. Tokyo Univ of Sci, Tokyo, Japan)
[2P-109]How are the subplate neurons positioned below the cortical plate in the developing mammalian cortex?
*Satoshi Yoshinaga1,2, Kazuhiro Ishii2, Mayumi Okamoto3, Takaki Miyata3, Ken-ichiro Kubo1,2, Kazunori Nakajima2 (1. Jikei Univ Sch Med, Tokyo, Japan, 2. Keio Univ Sch Med, Tokyo, Japan, 3. Grad Sch Med, Nagoya Univ, Nagoya, Japan)
[2P-110]Analysis of developmental and physiological roles of the nerve cord glial ependymal cells in the ascidian larva based on single-cell transcriptomes
*Ayana Maruo1, Miku Sotani2, Nanako Okawa2, Takeo Horie3, Takehiro G. Kusakabe1,2 (1. Dept Biol & Inst Integr Neurobiol, Konan University, 2. Grad Sch Nat Sci, Konan University, 3. Shimoda Mar Res Cntr, University of Tsukuba)
[2P-111]Histone lysine methyltransferase Setd8 regulates proliferation of retinal progenitor cells during retinal development
*Haruka Sekiryu1, Shuzo Matsubara1, Hisanobu Oda2, Taito Matsuda1, Kinichi Nakashima1 (1. Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2. Saiseikai Kumamoto Hospital, Division of integrative medical oncology, Department of cancer genome medicine)
[2P-112]Haploinsufficiency of Dab1 causes reduction of neocortical layer 1 thickness and splitting of caudal hippocampal CA1 pyramidal cell layer
*Takao Honda1,2, Yuki Hirota1, Kazunori Nakajima1 (1. Dept Anat, Sch Med, Keio Univ, Tokyo, Japan, 2. Lab Mol Bio, Gifu Pharm Univ, Gifu, Japan)
[2P-113]Roles of nicotinic acetylcholine receptors on the differentiation of pluripotent stem cell-derived primitive macrophages and dopaminergic neurons
*Koki Harada1, Takeshi Kato1, Masahiro Hirao1, Kaneyasu Nishimura1, Shun Shimohama2,3,4, Kazuyuki Takata1 (1. Div. Integ. Pharm. Sci., Kyoto Pharm. Univ., Kyoto, Japan, 2. Dept. Neurol., Sapporo Med. Univ. Sch. of Med., Sapporo, Japan, 3. Jiseikai Dementia Ctr., Tokyo, Japan, 4. Jiseikai Mem. Hosp., Tokyo, Japan)
[2P-114]Developmental formation of blood brain barrier in rat brains and the role of glial cells.
*Yukari Shigemoto Mogami1,2, Kimiko Nakayama Kitamura1, Kaoru Sato1 (1. Dept. Neuropharmacol. NIHS, 2. Dept. Neuropharmacol. Grad. Sch. Medicine, Yamanashi Univ.)
[2P-115]Epigenetic mechanisms regulating developmental stage-dependent change in cortical neural stem cell property.
*Takumi Nakagawa1, Takuya Imamura2, Sayako katada1, Kinichi Nakashima1 (1. Grad Sch Med Sci, Univ of Kyushu, Fukuoka, Japan, 2. Grad Sch Integrated Sci for life, Univ of Hiroshima, Hiroshima, japan)
[2P-116]Cell type-specific transcriptional control of Gsk3β in the development and evolution of the mammalian neocortex
*Tadashi Nomura1, Hitoshi Gotoh1, Hiroshi Kiyonari2, Katsuhiko Ono1 (1. Kyoto Prefectural University of Medicine, 2. RIKEN BDR)
[2P-117]Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during brain development
*Yugo Ishino1, Shoko Shimizu1, Masaya Tohyama1, Shingo Miyata1 (1. Kindai University)
[2P-118]Mouse hippocampal and neocortical neurons demonstrate different migration modes during brain development
*Ayako Kitazawa1,2, Satoshi Yoshinaga1,2, Minkyung Shin2,3, Kanehiro Hayashi2, Hitomi Sano2,4, Koji Oishi2,5, Ken-ichiro Kubo1,2, Kazunori Nakajima2 (1. Dept of Anat, Univ of Jikei, Tokyo, Japan, 2. Dept of Anat, Univ of Keio, Tokyo, Japan , 3. KBRI, Daegu, Korea, 4. SBI, Tokyo, Japan, 5. Grad Sch of Brain Sci, Univ of Doshisha, Kyoto, Japan)
[2P-119]Adult-neurogenesis at the hippocampal dentate gyrus is reduced in the magnetic field treated wild-type mice, and in untreated Abca1-null mice
*Maki Tsujita1, Hiroshi Takase1, Keito Furuie2, Motonari Tsubaki2,3, Natsuko Kumamoto1, Shinya Ugawa1 (1. Nagoya City University Graduate School of Medical Sciences, 2. Graduate School of Science and Technology, Kobe University, 3. Research Facility Center for Science and Technology, Kobe University)
[2P-120]Spatiotemporal gene expression and integration dynamics of neocortical layer 4 neurons revealed by temporal genetic fate-mapping
*Naoto Ohte1,2, Pei-Shan Hou2,4,5, Chihiro Nishiyama4, Carina Hanashima1,2,3,4 (1. Faculty of Education, Department of Science, Waseda University, Tokyo, Japan, 2. Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan, 3. Faculty of Education and Integrated Arts and Sciences, Waseda University, Tokyo, Japan, 4. Laboratory for Neocortical Development, RIKEN Center for Developmental Biology, Kobe, Japan, 5. National Yang Ming Chiao Tung University Institute of Anatomy and Cell Biology, Taipei, Taiwan)
[2P-121]A novel mechanism for morphological diversity of microglia mediated by HPRT
*Rinichiro Teruya1, Tomomi Okajima-Takahashi1, Kentaro Ueda2, Fuminori Tsuruta1 (1. Grad Sch Life and Env Sci, Univ of Tsukuba, Ibaraki, Japan, 2. Colleg of Biol Sci, Sch of Lif and Env Sci, Univ of Tsukuba, Ibaraki, Japan)
[2P-122]Dietary imbalance in polyunsaturated fatty acids during pregnancy affects dopaminergic neurogenesis in their embryos and is associated with offspring's various behavioral abnormalities
*Nobuyuki Sakayori1, Kazuki Fujii2, Masanori Katakura3, Kazuto Kobayashi4, Keizo Takao2, Makoto Sugita1 (1. Grad Sch Biomed Health Sci, Hiroshima University, Hiroshima, Japan, 2. Fac Med, Univ Toyama, Toyama, Japan, 3. Fac Pharmacy Pharmaceutical Sci, Josai Univ, Saitama, Japan, 4. Inst Biomed Sci, Fukushima Med Univ, Fukushima, Japan)
[2P-123]Analysis of the specific genes and laminae constructions of Retrosplenial cortex
*Misano Shirasaka1, Carina Hanashima1 (1. Grad Sch Advanced Science and Engineering, Waseda University, Tokyo, Japan)
[2P-124]Signalling mechanisms underlying SSRI-induced adult neurogenesis in the mouse hippocampus
*Yuki Higuchi1, Hiroyuki Arakawa1 (1. School of Medicine, University of the Ryukyus, Okinawa, Japan)
[2P-125]An endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus
*Naoya Murao1, Hideki Nishitoh1 (1. Dept of Med Sci, Univ of Miyazaki, Miyazaki, Japan)
[2P-126]Transcriptional and post-transcriptional mechanisms of Brn2-mediated upper-layer neurogenesis in the cerebral cortex
*Zi Chao Ngiam1, Carina Hanashima1 (1. Waseda University)
[2P-127]Function of the homeobox protein MEIS1 in cerebellar glial cells during cerebellar development
*Toma Adachi1, Kentaro Ichijo1, Tomoo Owa1, Satoshi Miyashita2, Yukiko Inoue1, Takayoshi Inoue1, Takuro Nakamura3, Mikio Hoshino1 (1. National center of Neurology and Psychiatry, 2. Brain Research Institute Niigata University, 3. Cancer Institute, Japanese Foundation for Cancer Research)
[2P-128]Calcium transients control a morphogenetic cycle underlying neuronal migratory movement
*Shin-ichiro Horigane1,2,3, Sayaka Takemoto-Kimura1,2,3,4, Satoshi kamijo3, Aki Adachi-Morishima3, Hajime Fujii3, Haruhiko Bito3 (1. Res Inst Envir Med, Nagoya Univ, Nagoya, Japan, 2. Grad Sch Med, Nagoya Univ, Nagoya, Japan, 3. Grad Sch Med, Univ of Tokyo, Tokyo, Japan, 4. PRESTO, Japan Science and Technology Agency, Saitama, Japan)
[2P-129]Nrf2-expressing pericytes acquire the traits of stemness
*Rika Sakuma1, Miku Kobayashi2, Rui Kobashi2, Mako Onishi2, Mitsuyo Maeda3,4, Yosky Kataoka3,4, Susumu Imaoka2 (1. Department of Anatomy and Cell Biology, Hyogo College of Medicine, 2. Sch of Biol and Environmental Sci, Kwansei Gakuin Univ, Hyogo, Japan, 3. Multi-Modal Microstructure Analysis Unit, RIKEN-JEOL Collaboration Center, Hyogo, Japan, 4. Laboratory for Cellular Function Imaging, RIKEN Center for Biosystems Dynamics Research)
[2P-130]Poststroke interaction between SVZ-derived NSPCs and regionally-induced iSCs within the ischemic area
*Akiko Nakano-Doi1,2, Hideaki Nishie1, Toshinori Sawano3, Takayuki Nakagomi1,2 (1. Hyogo College of Medicine, Hyogo, Jpan, 2. Department of Therapeutic Progress in Brain Diseases, Hyogo, Japan, 3. Department of Biomedical Sciences, Ritsumeikan University, Shiga, Japan)
[2P-131]Analysis of the phenotypic differences between Nestin-GFP mice genetically derived from C57BL/6 and CB-17 strain mice
*Hideaki Nishie1,4, Akiko Nakano-Doi1,2, Toshinori Sawano3, Takayuki Nakagomi1,2 (1. Institute for Advanced Medical Sciences, Hyogo College of Medicine, 2. Department of Therapeutic Progress in Brain Diseases, Hyogo College of Medicine, 3. Department of Biomedical Sciences, Ritsumeikan University, 4. Nippon Zoki Pharmaceutical Co., Ltd.)
[2P-132]LDN193189 induces iSCs to neural stem cell-like cells
*Yusuke Minato1, Akiko Nakano-Doi2, Sachi Kuwahara-Otani3, Seishi Maeda1, Tomohiro Matsuyama4, Takayuki Nakagomi2, Hideshi Yagi1 (1. Dept Anat and Cell Biol, Hyogo Col of Med, Hyogo, Japan, 2. Inst Adv Med Sci, Hyogo Col of Med, Hyogo, Japan, 3. Gen Edu Ctr, Hyogo Univ of Health Sci, Hyogo, Japan, 4. Dept Therap Progress in Brain Deiseases, Hyogo Col of Med, Hyogo, Japan)
[2P-133]Expression level of the reprogramming factor NeuroD1 is critical for neuronal conversion efficiency from glial cells
*Kanae Matsuda1, Taito Matsuda1, Kinichi Nakashima1 (1. Kyushu University)
[2P-134]Reduction of Setd8 expression is implicated in the age-related NSC dysfunction in the mouse hippocampus
*Shuzo Matsubara1, Taito Matsuda1, Haruka Sekiryu1, Hiroyoshi Doi1, Takumi Nakagawa1, Hisanobu Oda2, Kinichi Nakashima1 (1. Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2. Saiseikai Kumamoto Hospital, Division of integrative medical oncology, Department of cancer genome medicine)
[2P-135]Isolation of pituitary stem/progenitor cells from human pluripotent stem cells-derived hypothalamic-pituitary organoid.
*Aoi Nonoyama1,2, Miho Kawata2, Yu Kodani2, Toshiki Kameyama2, Kanako Saito2, Hidetaka Suga3, Hiroshi Nagasaki2 (1. Grad Sch Med, Fujita Health University, Aichi, Japan, 2. Department of Physiology, School of Medicine, Fujita Health University, Aichi, Japan, 3. Department of Endocrinology and Diabetes, Grad Sch Med, Nagoya University, Aichi, Japan)
[2P-136]Generation and single-cell level characterization of neurons directly differentiated from human T lymphocytes
*Yoichi Saito1, Mitsuru Ishikawa1, Jonathan Moody2, Chung Chau Hon2, Jay Woo Shin2, Wado Akamatsu3, Hideyuki Okano1 (1. Keio Univ Sch Med, Tokyo, Japan, 2. RIKEN, IMS, Kanagawa, Japan, 3. Sch Med, Juntendo Univ, Tokyo, Japan)
[2P-137]Klf5 gene effects on cell cycle, differentiation and proliferation of embryonic neural stem cells
*Anri Kuroda1, Yoshitaka Hayashi1, Takahiro Fuchigami, Hiroaki Kitagawa1, Masatsugu Ema2, Hitoshi Seiji1 (1. Shiga University of Medical Science Integrative Phisioilogy, Shiga, Japan, 2. Shiga University of Medical Science Research Center for Animal Life Science, Shiga, Japan )
[2P-138]Ras-GAPs Control Neuronal Circuit Development in the Barrel Cortex Layer 4
*Madhura Subba Rao1,2, Hiromi Mizuno1,2, Takuya Sato3, Takuji Iwasato3,4, Hidenobu Mizuno1,2 (1. Laboratory of Multi-dimensional Imaging, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto 860-0811, Japan, 2. Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-0811, Japan, 3. Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima 411-8540, Japan, 4. Department of Genetics, SOKENDAI, Mishima 411-8540, Japan)
[2P-139]Timothy Syndrome-associated Cav1.2 mutations and DEE11-associated Nav1.2 mutations impair neuronal circuit formation in different manners in mouse neocortex
*Nao Nakagawa Tamagawa1,2, Kohtaroh Sugao3, Hidetaka Nagata3, Yoshiaki Tagawa1 (1. Grad Sch Med Dent Sci, Kagoshima Univ, Japan, 2. RIKEN CBS, Japan, 3. Platform Technology Research Unit, Sumitomo Dainippon Pharma Co., Ltd., Japan)
[2P-140]Robo1 signaling-mediated Golgi apparatus dynamics determine the dendritic morphology of layers 2/3 pyramidal neurons in the cerebral cortex
*Yuko Gonda1,3, Carina Hanashima2,3 (1. Dept. Histol. Neuroanat., Tokyo Med. Univ., Tokyo, Japan, 2. Lab. Dev. Biol., Waseda Univ., Tokyo, Japan, 3. Lab. Neocort. Dev., RIKEN CDB, Kobe, Japan )
[2P-141]Type II classic cadherins redundantly ensure the early circuit board formation for intricate neural network wiring
*Takayoshi Inoue1, Kou Hiraga1 (1. National Center of Neurology and Psychiatry)
[2P-142]Signal Regulatory Protein alpha (SIRPα) is involved in the dendritic growth of cortical pyramidal neurons through the phosphorylation and dephosphorylation of Tyr501 residue
*Fumio Nakamura1, Miyu Wakatsuki1, Kohtaro Takizawa1, Aoi Jitsuki-Takahashi1 (1. Tokyo Women's Medical University)
[2P-143]Dendritic development of newborn neurons in the postnatal olfactory bulb is regulated by Sema3E-PlexinD1-RhoJ signaling
*Masato Sawada Sawada1,2, Ayato Hamaguchi1, Naomichi Mano1, Akiyoshi Uemura3, Kazunobu Sawamoto1,2 (1. Dept Dev Regen Neurobiol, Inst Brain Sci, Nagoya City Univ Grad Sch Med Sci, Nagoya, Japan, 2. Div Neural Dev Regen, NIPS, Okazaki, Japan, 3. Dept Retinal Vasc Biol, Nagoya City Univ Grad Sch Med Sci, Nagoya, Japan)
[2P-144]Formation of Purkinje cell clusters in the murine embryonic cerebellum
*Yuanjun Luo1,3, Khoa Anh Tran4, Tatsumi Hirata2, Izumi Sugihara1 (1. Tokyo Med and Dent Univ, Tokyo,Japan, 2. Nat Inst of Gene,Mishima, Japan, 3. Japan Soc for the Prom of Sci,Tokyo, Japan, 4. Har Med Sch,Boston, USA)
[2P-145]Abundant oleoyl-lysophosphatidylethanolamine in brain exerts stimulation of neurite outgrowth and protection against glutamate toxicity in cultured cortical neurons
*William Aoi Omi1,2, Kazutoshi Hisano2,3, Hironori Yoshida1,2, Shiori Kawase4, Tetsuhiko Mimura2,3, Fumiaki Makiyama2,3, Ryoya Nakada1,2, Hisao Haniu1,2,3, Tamotsu Tsukahara5, Taiga Kurihara6, Yoshikazu Matsuda7, Naoto Saito1,2,3, Takeshi Uemura1,2,3,4 (1. Grad. Sch. of. Sci. & Tech., Shinshu Univ., Nagano, Japan, 2. IBS-ICCER, Shinshu Univ, Nagano, Japan, 3. Grad. Sch. of. Med., Sci. & Tech., Shinshu Univ., Nagano, Japan, 4. Div. of Gene Res., Res. Cent. for Advanced Sci., Shinshu Univ, Nagano, Japan, 5. Dept. Pharmacol. Therap. Innov, Nagasaki Univ., Inst. Biomed. Sci., Nagasaki, Japan, 6. Div.Microbiol. & Mol. Cell. Biol. Nihon Pharmaceutical Univ, Saitama, Japan, 7. Div. Clinical Pharmacol., Nihon Pharmaceutical Univ, Saitama, Japan)
[2P-146]Exploring the dendritic refinement dynamics of cortical neurons via in vivo high spatiotemporal-resolution imaging
*Luwei Wang1,2, Shingo Nakazawa1,3, Hidenobu Mizuno4, Takuji Iwasato1,2 (1. Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, 2. Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Mishima, 3. Department of Basic Neurosciences, University of Geneva, Switzerland, 4. International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan)
[2P-147]Secreted phospholipase A2 group V expressed by radial glia modulates LysoPtdGlc/GPR55-mediated nociceptive axon guidance in spinal cord development
*Adam T. Guy1,2, Mariko Inoue2, Yoshio Hirabayashi3,4, Kei Hanafusa4, Mitsuaki Yanagida4, Kazuhisa Iwabuchi4, Kei Yamamoto5, Makoto Murakami6, Hiroyuki Kamiguchi2,7 (1. Grad Sch of Biostudies, Kyoto University, Kyoto, Japan, 2. Neural Cell Dynamics Lab, RIKEN CBS, Wako, Japan, 3. Cellular Informatics Lab, RIKEN CPR, Wako, Japan, 4. Institute for Environmental and Gender-Specific Medicine, Grad Sch of Medicine, Juntendo University, Tokyo, Japan, 5. Grad Sch of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan, 6. Center for Disease Biology and Integrative Medicine, Grad Sch of Medicine, University of Tokyo, Tokyo, Japan, 7. AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan)
[2P-148]Morphological analyses for mitochondrial localization in the axon initial segments (AIS) of nerve injured-motor neuron and microglial activation around AIS
*Hiromi Tamada1, Sumiko Kiryu-Seo1, Sohgo Sawada1, Hiroshi Kiyama1 (1. Nagoya University)
[2P-149]Cellular excitability and formation of the corpus callosum during development of the cerebral cortex
*Rei Ota1, Masayoshi Okada2, Tetsuji Mori1 (1. Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, Yonago City, Tottori, Japan, 2. Department of Medical Life Science, College of Life Science, Kurashiki University of Science and the Arts,Kurashiki, Okayama, Japan)
[2P-150]Effect of DEAF1 gene abnormalities on cortical neurons in mouse brain development
*Takuma Nishijo1, Koh-ichi Nagata1 (1. Institute for Developmental Research, Aichi Developmental Disability Center, Aichi, Japan)
[2P-151]Divergent functions of G protein-coupled receptor 3 in neurite outgrowth, polarity formation, survival, and axonal regeneration in neurons
*Shigeru Tanaka1, Shun Masuda1,2, Naoto Shimada1, Hiroko Shiraki1, Tatsuhiro Miyagi1, Kana Harada1, Izumi Hide1, Norio Sakai1 (1. Dept Mol & Pharma Neurosci, Grad Sch Med, Univ of Hiroshima, Hiroshima, Japan, 2. Dept ophthal, Grad Sch Med, Univ of Hiroshima, Hiroshima, Japan)
[2P-152]Molecular mechanism of protein tyrosine phosphatase and heparan sulfate proteoglycan-mediated axon collateral formation
*Misato Yasumura1, Tokuichi Iguchi1,2, Makoto Sato1,3 (1. Grad Sch Med, Osaka University, Osaka, Japan, 2. Dept Nursing, Fac Health Sci, Fukui Health Sci Univ, Fukui, Japan, 3. Div Dev Neurosci, United Grad Sch Child Dev, Osaka Univ, Osaka, Japan)
[2P-153]Sema6A-PlxnA2/A4 signaling regulate the projection and collateral branch formation of olfactory bulb axons
*Takahiko Kawasaki1, Tatsumi Hirata1 (1. National institute of genetics)
[2P-154]Social stress-induced synapse remodeling in the somatosensory thalamus
*Hisako Nakayama1, Mariko Miyata1 (1. Tokyo Women's Medical University)
[2P-155]Functional and morphological changes of the presynapse at the developing somatosensory thalamus
*Mitsuharu Midorikawa1, Mariko Miyata1 (1. Tokyo Women's Medical University)
[2P-156]Synchronous firing promotes formation of synaptic connections
*Tetsuhiko Kashima1, Yuji Ikegaya1,2,3 (1. Lab Chem Pharmacol, Grad Sch Pharmaceut Sci, Univ Tokyo, Tokyo, Japan, 2. Inst AI Beyond, Univ Tokyo, Tokyo, Japan, 3. CiNet, Suita, Osaka)
[2P-157]Elimination of cortico-motoneuronal synapses during development in rodents
*Takae Ohno1, Satoshi Fukuda1, Kenji Sakimura2, Masaki Sakurai1 (1. Teikyo Univ.Sch.Med., 2. Brain Research Institute, Niigata Univ.)
[2P-158]Assessment of glial cells on the development of calyx-MNTB synapse in the Hapln4-deficient mice
*Toshitaka Oohashi1, Yuichi Tani1, Haruko Miyazaki1, Kojiro Nojima1, Himeno Kaneshiro1, Tetsuya Hori2 (1. Grad Sch Med Dent Pharm Sci, Okayama University, Okayama, Japan, 2. Okinawa Inst of Sci and Tech Grad, Okinawa, Japan)
[2P-159]Early postnatal developmental period for ASD-related social behavioral circuits
*Goichi Miyoshi1 (1. Grad Sch Med, Gunma Univ, Japan)
[2P-160]Somatosensory neural circuit refinement revealed by brainstem NMDAR deficient mice
*Chiemi Kimura-Nakajima1,2, Ayumi Suzuki1,2, Takuji Iwasato1,2 (1. Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, Shizuoka, Japan, 2. Department of Genetics, SOKENDAI, Mishima, Shizuoka, Japan)
[2P-161]Synaptic turnover and inter-synapse interactions in the dorsomedial prefrontal cortex of autism model marmosets
*Jun NOGUCHI1, Satoshi WATANABE1, Risa ISODA1, Keiko NAKAGAKI1, Kazuhisa SAKAI1, Eriko SUGANO2, Hiroshi TOMITA2, Akiya WATAKABE3, Tetsuo YAMAMORI3, Hiroaki MIZUKAMI4, Noritaka ICHINOHE1 (1. National Center of Neurology and Psychiatry, Tokyo, Japan, 2. Grad Course Biol Sci, Iwate University, Iwate, Japan, 3. Center Brain Sci, RIKEN, Saitama, Japan, 4. Div Genet Therapeutics, Jichi Med Univ, Tochigi, Japan)
[2P-162]Presynaptic supervision of cortical synaptic plasticity in motor skill learning
*Jaerin Sohn1, Yasuo Kawaguchi1,2,3, Yoshiyuki Kubota1,2 (1. National Institute for Physiological Sciences (NIPS), Aichi, Japan, 2. Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Aichi, Japan, 3. Brain Science Institute, Tamagawa University, Tokyo, Japan)
[2P-163]Ectopic formation of perineuronal nets by overexpressing aggrecan in cortical pyramidal neurons
*Shinji Miyata1, Ryuto Ashino1, Ayumu Mubuchi1 (1. Grad Sch Agr, Tokyo Univ Agr and Tech)
[2P-164]Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition
*Hiroyoshi Doi1,2, Matsuda Taito1, Ken Yamaura2, Kinichi Nakashima1 (1. Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2. Department of Anesthesiology and Critical Care Medicine, Graduate school of Medical Sciences, Kyushu University)
[2P-165]Functional contributions of a neanderthal GLI3 variant to various human traits
*Ako Agata1, Hitoshi Gotoh1, Katsuhiko Ono1, Tadashi Nomura1 (1. Kyoto Prefectural University of Medicine)
[2P-166]RNA helicase Ddx20 in oligodendrocytes contributes to neuronal survival in the central nervous system
*Norihisa Bizen1, Anna Simankova1, Hirohide Takebayashi1,2 (1. Dev Neurobiol Anat, Grad Sch Med Dent, Niigata Univ, Niigata, Japan, 2. CCRF, Niigata Univ, Niigata, Japan)
[2P-167]Induction of neural differentiation in hybrid organoids formed by co-culture system of human induced pluripotent stem cells
*Kaoru Suzuki1, Masashi Ikeuchi2, Shuji Hayashi1 (1. Res Inst Found Glob Health Care, Nagoya, Japan, 2. Division of Biofunct Restorat Inst Biomaterials Bioengineer Tokyo Med Dent Univ, Tokyo, Japan)
[2P-168]Excitatory synapse maturation in transcription factor-induced human iPSC-derived neurons
*Waka Lin1, Saki Yamada1, Hikaru Watanabe1, Yudai Kawashima1, Shusaku Shiomoto1, Yuko Sekino2 (1. Biomed R&D Dept, Ricoh Company, Ltd., Kanagawa, Japan, 2. Grad Sch Ph Sci, Univ of Tokyo, Tokyo, Japan)
[2P-169]Functional comparison between human fetal astrocytes and human iPS cell-derived astrocytes produced by rapid differentiation technology.
*Yuki Kaga1, Tatsuya Sameshima1, Shinnosuke Koshizuka1, Manabu Seo2, Tomoyuki Aratani1, Motoki Azuma1 (1. RICOH Co., Ltd., 2. Elixirgen Scientific, Inc.)
[2P-170]Development of an In Vitro Platform to Control iPSC Differentiation by Morphogen Gradient
*Isabel Siew Yin Koh1, Masaya Hagiwara1 (1. Cluster for Pioneering Research, RIKEN, Wako, Japan)
[2P-171]An in vitro non-human primate brain model using assembloids derived from embryonic stem cells
*Tomoki Kodera1, Taiki Hara1, Nao Morimoto1, Ryosuke Takeuchi1, Fumitaka Osakada1,2,3,4 (1. Grad Sch Pharmaceutical Sci, Nagoya univ, Aichi, Japan, 2. Inst for Adv Res, Nagoya univ, Aichi, Japan, 3. Inst of Nano-Life-Systems, Inst of Innovation for Future Society, Nagoya univ, Aichi, Japan, 4. Inst for Glyco-core Res, Nagoya univ, Aichi, Japan)
[2P-172]A platform for disease analysis based on a method for differentiation of human iPS cells into subtype-specific neurons
*Mitsuru Ishikawa1, Emi Qian1, Hideyuki Okano1 (1. Keio University)
[2P-173]Single-cell RNA analysis in vascularized human cortical organoids utilizing a public database
*Yuya Sato1, Toru Asahi1,2,3, Kosuke Kataoka3 (1. Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan, 2. Research Organization for Nano & Life Innovation, Waseda University, Tokyo, Japan, 3. Comprehensive Research Organization, Waseda University, Tokyo, Japan)
[2P-174]The subcommissural organ maintains features of neuroepithelial cells in the adult mouse
*Hitoshi Inada1,2, Laarni Grace Corales2, Kotaro Hiraoka3, Noriko Osumi2 (1. Grad Sch Biomed Eng, Tohoku Univ, Japan, 2. Grad Sch Med, Tohoku Univ, Japan, 3. Cyclo and Radio Center, Tohoku Univ, Japan)
[2P-175]The alteration of astrocytes in cross-modal plasticity
*Ikuko Takeda1,2 (1. Department of Anatomy and Molecular Cell Biology, Grad Sch Med, Nagoya university, Nagoya, Japan, 2. Division of Multicellular Circuit Dynamics, National Institute for Physiological Sciences)
[2P-177]Regulation of N-cadherin trafficking by a secretory glycoprotein Reelin
*Kanehiro Hayashi1, Ken-ichiro Kubo1,2, Nobuhiko Nakao3,4, Taiji Adachi3,4, Kazunori Nakajima1 (1. Keio University School of Medicine, 2. The Jikei University School of Medicine, 3. Graduate School of Engineering, Kyoto University, 4. Institute for Frontier Life and Medical Sciences, Kyoto University)
[2P-178]Potential role of IGFBP (insulin-growth factor binding protein) domain in japanese newt (Cynops pyrrhogaster) regeneration
*Karen Wakamatsu1,2, Joshua Kai Karpelowitz1, Toshiyuki Tsuji2, Pavel Prosselkov1 (1. Manai Institute of Science and Technology, 2. Mita International School)