[2S03a] Symposium Organized by the Recipient of the 7th JSN Distinguished Investigator AwardNeurodegenerative/neuropsychiatric diseases caused by nucleic acidrepeat expansion -from disease mechanism to future therapy- | NEURO2022

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[2S03a]Symposium Organized by the Recipient of the 7th JSN Distinguished Investigator Award
Neurodegenerative/neuropsychiatric diseases caused by nucleic acidrepeat expansion -from disease mechanism to future therapy-

Fri. Jul 1, 2022 2:00 PM - 4:00 PM JST
Fri. Jul 1, 2022 5:00 AM - 7:00 AM UTC

Room 3 Conference Building B1 (Okinawa Convention Center)

Chair: KOHJI MORI

[2S03a-01]Elucidation of regulatory mechanisms of RAN translation using C9-ALS/FTD fly model

*Yuzo Fujino^1,2, Morio Ueyama¹, Toshiki Mizuno², Yoshitaka Nagai¹ (1. Department of Neurology, Kindai University Faculty of Medicine, 2. Department of Neurology, Kyoto Prefectural University of Medicine)

[2S03a-02]Alleviation of RNA toxicity by a small molecule targeting UGGAA repeat in spinocerebellar ataxia type 31

*Tomonori Shibata¹, Konami Nagano², Morio Ueyama³, Kensuke Ninomiya⁴, Tetsuro Hirose⁴, Yoshitaka Nagai³, Kinya Ishikawa⁵, Gota Kawai², Kazuhiko Nakatani¹ (1. SANKEN, Osaka Univ, 2. Fac of Eng, Chiba Inst of Tech, 3. Sch of Med, KINDAI Univ, 4. FBS, Osaka Univ, 5. Tokyo Med & Dent Univ)

[2S03a-03]DNA damage repair impairment in C9orf72-FTD/ALS

*Yoshihiro Nihei¹ (1. Keio University School of Medicine)

[2S03a-04]Order controls disordered droplets: structure-function relationships in C9ORF72-derived poly(PR)

*Kohsuke Kanekura¹, Yuhei Hayamizu², Masahiko Kuroda¹ (1. Tokyo Medical University, 2. Tokyo Insitute of Technology)

[2S03a-05]The cellular functions of G-quadruplex in neurological diseases

*Norifumi Shioda¹ (1. Kumamoto University, IMEG, Japan)

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