Session Details
[4O05m1]Neurodegenerative Disorders 2
Sun. Jul 3, 2022 9:00 AM - 10:00 AM JST
Sun. Jul 3, 2022 12:00 AM - 1:00 AM UTC
Sun. Jul 3, 2022 12:00 AM - 1:00 AM UTC
Room 5 Conference Building B2 (Okinawa Convention Center)
Chair: Youichi Shinozaki (University of Yamanashi)
[4O05m1-01]Ethosuximide improves clinical and pathological phenotypes of SCA42 mouse model
*Masaki Okubo1, Hiroshi Doi1, Shunta Hashiguchi1, Misako Kunii1, Keita Takahashi1, Mikiko Tada1, Kenichi Tanaka1, Hideyuki Takeuchi1, Taro Ishikawa2, Fumiaki Tanaka1 (1. Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, 2. Department of Pharmacology, The Jikei University School of Medicine)
[4O05m1-02]ABCA1 deficiency in astrocytes triggers non-cell-autonomous optic neuropathy via neuroinflammation and excitotoxicity
*Youichi Shinozaki1,2, Alex Leung3, Kazuhiko Namekata4, Nobuhiko Ohno5,6, Eiji Shigetomi2,1, Kenji Kashiwagi7, Takayuki Harada4, Shin-Ichi Ohnuma3, Schuichi Koizumi1,2 (1. Dept Neuropharmacol, Grad Sch Med, Univ Yamanashi, Yamanashi, Japan, 2. GLIA Cent, Grad Sch Med, Univ Yamanashi, Yamanashi, Japan, 3. UCL Inst Ophthalmol, UCL, London, UK, 4. Vis Res Project, Tokyo Metr Inst Med, Tokyo, Japan, 5. Div Ultrastract Res, Natl Inst Physiol Sci, Aichi, Japan, 6. Div Anatomy, Jichi Med Univ, Tochigi, Japan, 7. Dept Ophthalmol, Interdisp Grad Sch Med, Univ Yamanashi, Yamanashi, Japan)
[4O05m1-03]Disruption of mitochondria-associated membrane inactivates TANK-binding kinase 1, leading to impairment of stress granule formation and motor dysfunction
*Seiji Watanabe1, Kotaro Oiwa1,2, Koji Yamanaka1 (1. RIEM, Nagoya Univ, Aichi, Japan, 2. Grad Sch Med, Nagoya Univ, Aichi, Japan)
[4O05m1-04]Molecular mechanism of immune-mediated neuronal cell death and its relevance to pathogenesis of neurodegenerative diseases
*Fumio Takahashi1,3, Chenyang Zhang1, Hirohiko Hohjoh2, Ben Raveney1, Takashi Yamamura1, Nobuhiro Hayashi3, Shinji Oki1 (1. Dept. of Immunol., Natl Inst Neurol. NCNP, 2. Dept. of Mol Pharmacol., Natl Inst Neurol. NCNP, 3. Grad. Sch. of Life Sci and Technol., Titech)