Presentation Information

[2TS12a-02]TBK1 activates immunoproteasome via IFNβ and suppresses accumulation of aggregation-prone monomeric TDP-43 and its phosphorylated form

*Shohei Sakai1, Okiru Komine1, Seiji Watanabe1, Kotaro Oiwa1,2, Koji Yamanaka1 (1. Dept of Neurosci and Pathobiol, RIEM, Nagoya Univ, Aichi, Japan, 2. Dept of Neurol, Nagoya Univ, Aichi, Japan)

Keywords:

amyotrophic lateral sclerosis (ALS),TDP-43,TBK1,IFNβ

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