Presentation Information
[2TS12m-04]eIF5 stimulates RAN translation from the CUG codon of aberrantly elongated GGGGCC repeat sequence in C9orf72 gene.
*Shiho GOTOH1, Kohji Mori1, Yuzo Fujino 2,3, Yuya Kawabe1, Tomoko Yamashita 1, Tsubasa Omi 1, Kenichi Nagata4, Shinji Tagami1, Yoshitaka Nagai2, Manabu Ikeda1 (1. Psychiatry, Grad Sch Med, Osaka Univ, Suita, Japan , 2. Neurology, Kindai Univ Faculty of Med, Osaka-Sayama, Japan , 3. Neurology, Kyoto Prefectural Univ Med, Kyoto, Japan , 4. Precision Medicine for Dementia, Grad Sch Med, Osaka Univ, Suita, Japan )
Keywords:
RAN translation,C9orf72,eIF,FTLD
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