Presentation Information
[AP-01-6]Parkinson's disease-linked PSAP gene mutation affects progranulin trafficking and GCase activity
Ryo Wakamori1, Yutaka Oji1, Taku Hatano1, Kentaro Gejima1, Mitsuhiro Kitagawa1, Ayami Okuzumi1, Yoko Imamichi-tatano1, Risa Nonaka3, Shin-ichi Ueno1, Kahori Shiba-fukushima2, Kei-ichi Ishikawa4, Yukiko Sasazawa5, Wado Akamatsu4, Masaya Imoto6, Nobutaka Hattori1,7 (1.Department of Neurology, Juntendo University Faculty of Medicine, Japan, 2.Department of Drug Development for Parkinson's Disease, Juntendo University Graduate School of Medicine, Japan, 3.Juntendo University Faculty of Pharmacy, Japan, 4.Center for Genomic and Regenerative Medicine, Graduate School of Medicine, Juntendo University, Japan, 5.Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Japan, 6.Division for Development of Autophagy Modulating Drugs, Juntendo University Faculty of Medicine, Japan, 7.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan)