Presentation Information
[1P-036]Cerebellar Resilience to Amyloid pathology associates with Microglial-ECM Proteoglycan Interactions in 5xFAD Mice
*Carla Cangalaya1, Henning Peter Düsedau2, Ildiko Rita Dunay2,3,4, Alexander Dityatev1,3,5, Stoyan Stoyanov1 (1. Molecular Neuroplasticity Research Group, German Center for Neurodegenerative Diseases (DZNE), D-39120, Magdeburg, Germany., 2. Institute of Inflammation and Neurodegeneration, Health Campus Immunology, Infectiology and Inflammation (GC-I3), Otto-von-Guericke-University, D-39120, Magdeburg, Germany., 3. Center for Behavioral Brain Sciences (CBBS), D-39106 Magdeburg, Germany., 4. German Center for Mental Health (DZPG) Center for Intervention and Research on Adaptive and Maladaptive Brain Circuits Underlying Mental Health (C-I-R-C), Halle-Jena-Magdeburg, Germany. , 5. Medical Faculty, Otto-von-Guericke-University, D-39120, Magdeburg, Germany.)
Keywords:
Microglia,Alzheimer’s disease,Extracellular matrix,Cerebellum
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