[1P] Poster

[1P-042] De novo mutation of SRF coactivator MRTFB found in patients with autism spectrum disorders and intellectual disability negatively and positively regulates their function, respectively

*Daisuke Ihara¹, Momoko Ishikuro¹, Kyoko Kobayashi¹, Ryotaro Oishi¹, Yuya Yamazaki¹, Natsumi Satou¹, Ichiro Takasaki², Mamoru Fukuchi³, Masaaki Tsuda¹, Akiko Tabuchi¹ (1. Grad Sch Med & Pharm Sci, Univ of Toyama, Toyama, Japan, 2. Dep Pharmacol, Grad Sch Sci & Eng, Grad Sch Innov Life Sci, Univ of Toyama, Toyama, Japan, 3. Lab Mol Neurosci, Fac Pharm, Takasaki Univ of Health & Welfare, Gunma, Japan)

Keywords:

MRTF,SRF,gene expression,dendritic morphology

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