[1P] Poster

[1P-073] Activation of adult neurogenesis improves amyloid-β pathology and cognitive function through coordinated non-cell-autonomous, AMPK-dependent metabolic reprogramming in Alzheimer’s disease model mice

*Masahiro Fukui¹, Takashi Kaise², Taimu Masaki^1,4, Tyler Sakamoto³, Ryoichiro Kageyama¹ (1. RIKEN Center for Biosystems Dynamics Research, 2. Massachusetts Institute of Technology, Cambridge, MA, 02139 USA, 3. Stanford University School of Medicine, Stanford, CA, 94305 USA, 4. Graduate School of Medicine, Kyoto University)

Keywords:

Adult neurogenesis,Alzheimer's disease,Metabolic reprogramming,AMPK signaling

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