Presentation Information

[1P-407]α6GABAA receptor-selective positive allosteric modulator as a potential novel therapy for autism spectrum disorder: A preclinical study in Fmr1 KO mice

*Yu-Hsuan Lee1, Dishary Sharmin3, James Cook3, Shu-Ling Chiu4, Lih-Chu Chiou1,2 (1. National Taiwan University, College of Medicine, Taipei, Taiwan , 2. Grad Institute of Brain and Mind Sci., College of Med, National Taiwan Univ, Taipei, Taiwan, 3. Dept of Chemistry and Biochem., Univ. of Wisconsin-Milwaukee, Milwaukee, WI, USA, 4. Inst. of Cell. and Organismic Biol., ICOB, Academia Sinica, Taipei, Taiwan)

Keywords:

Autism Spectrum Disorder,GABAergic Transmission,Cerebellum,α6 subunit-containing GABAA receptor

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