[1S03m] The Multilayered Role of the Nuclear Lamina in Brain Formation, Disease, and Aging

[1S03m-03] Developing neurons generate transient DNA damage by mechanostress during migration in crowded neural tissue

*Mineko Kengaku¹, Zhejing Zhang¹, Andres Canela¹, Takumi Kawaue^2,1, Naotaka Nakazawa^3,1, Takahiro Furuta⁵, Yusuke Kishi⁴, Hiroyuki Sasanuma⁶ (1. KUIAS-iCeMS, Kyoto University, Kyoto Japan, 2. Grad Sch Med, Nagoya Univ, Nagoya, Japan, 3. Grad Sch Sci&Eng, Kindai Univ, Osaka, Japan, 4. Inst. Quant Biosci, Univ of Tokyo, Tokyo, Japan, 5. Grad Sch Dent, Osaka Univ, Osaka, Japan, 6. Tokyo Metro Inst Med Sci, Tokyo, Japan)

Keywords:

neuronal migration,DNA double strand break,mechanostress,nucleus

Password required to view

A password is required to view the abstracts.
The password can be found on your name badge (participation certificate).