[1S04a] The Origin, Mechanisms, Functions of Sleep

[1S04a-01] Bidirectional modulation of sleep and wakefulness via prefrontal cortical chemogenetics

*Lukas Krone^1,2,3, Jack D. Hamilton^1,2,4,5, Anna Hoerder-Suabedissen^2,4,5, Clara Marnitz^1,2, Anna Szabo⁴, Colin J. Akerman⁶, Zoltán Molnár², Vladyslav V. Vyazovskiy^2,4,5 (1. Centre for Neural Circuits and Behaviour, University of Oxford, Oxford, UK, 2. Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK, 3. University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland, 4. Sir Jules Thorn Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK, 5. Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK, 6. Department of Pharmacology, University of Oxford, Oxford, UK)

Keywords:

sleep,prefrontal cortex,chemogenetics,homeostasis

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