[2P] Poster

[2P-144] A Synthetic Synapse Organizer Promotes Recovery of Hand Dexterity in Spinal-Injured Macaques By Extensive Corticospinal Re-organization

*Stefan Peyda¹, Reona Yamaguchi^1,2, Satoko Ueno^1,2, Kaoru Isa¹, Kunimichi Suzuki^3,4,5, Veronica T. Chang⁵, Kenta Kobayashi⁶, Satoko Hattori⁷, Hiroyuki Sasakura⁷, Keiko Matsuda^3,4, Kosei Takeuchi⁷, A. Radu Aricescu^3,5, Hirotaka Onoe^8,9, Michisuke Yuzaki^3,4, Tadashi Isa^1,2,8,10 (1. Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan, 3. Human Biology Microbiome Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan, 4. Department of Neurophysiology, School of Medicine, Keio University, Tokyo, Japan, 5. MRC Laboratory of Molecular Biology, Cambridge, United Kingdom , 6. Section of Viral Vector Development, National Institute for Physiological Sciences, Okazaki, Japan, 7. Division of Neurobehavioral Therapeutics, Intl. Center of Brain Science, Fujita Health University, Toyoake, Japan, 8. Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 9. Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Kobe Gakuin, Kobe, Japan, 10. National Institute for Physiological Sciences, Okazaki, Japan)

Keywords:

Spinal cord injury,non-human primate,synapse organizer,neuroplasticity

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