Presentation Information
[2P-362]Humanized MAPT and APP Increase Neuronal Excitability and Accelerate Phosphorylated Tau Propagation in a Novel Entorhinal Cortex Layer II–Targeted Mouse Model of Early Alzheimer’s Disease
*Ayaka Hagita-Tatsumoto1, Arun Reddy Ravula1, Brendan Gibbs1, Justice Ellison1, Nibedita Basu Ray1, Alejandro Longtree-Preciado1, Seiko Ikezu1, Tsuneya Ikezu1 (1. Dept of Neuroscience, Mayo Clinic, Florida, United States)
Keywords:
ALZHEIMER'S DISEASES,TAU PROPAGATION,NEURONAL EXCITABILITY,MOUSE MODEL
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