Presentation Information

[2P-384]Oligonucleotide modulation of FUS phase separation as a therapeutic strategy for ALS and FTLD

*Mohammad Moniruzzaman1, Yusuke Fujioka 1, Akihide Takeuchi 2, Akio Masuda 3, Masahiro Neya 4, Yohei Okada 5, Shinsuke Ishigaki 1 (1. Molecular Neuroscience Research Center, Shiga Univ of Med Sci, 2. Dept of Dev Biol and Func Genomics, Ehime Univ Grad Sch of Med Sci, 3. Center for Neuro Dis and Cancer, Nagoya Univ Grad Sch of Med, 4. KNC Laboratories Co., Ltd, 5. Inst for Med sci of Aging, Aichi Med Univ)

Keywords:

ALS,Fused in sarcoma (FUS),Liquid-liquid phase separation (LLPS),RNA therapeutics

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