[2P] Poster

[2P-392] TBK1-IFNβ-immunoproteasome axis is a neuron-specific molecular pathway to alleviate TDP-43 pathology in ALS

*Shohei Sakai¹, Kotaro Oiwa^1,2, Yohei Iguchi³, Seiji Watanabe^1,4, Okiru Komine¹, Mai Horiuchi¹, Masahisa Katsuno³, Koji Yamanaka¹ (1. Dept Neurosci Pathobiol, RIEM, Nagoya Univ, Nagoya, Japan, 2. Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, USA, 3. Dept Neurology, Grad Sch Med, Nagoya Univ, Nagoya, Japan, 4. Dept Life Science, Faculty of Medicine, Shimane Univ, Izumo, Japan)

Keywords:

ALS,TDP-43,TBK1,proteasome

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