[3O02e] Disorders of the Nervous System 6

[3O02e-06] Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome

*Akisa Nemoto^1,2, Kent Imaizumi¹, Fuyuki Miya³, Yuka Hiroi², Mamiko Yamada^3,4, Hirosato Ideno¹, Shinji Saitoh⁵, Kenjiro Kosaki³, Hironobu Okuno^1,2, Hideyuki Okano¹ (1. Department of Physiology, Keio University School of Medicine, 2. Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, 3. Center for Medical Genetics, Keio University School of Medicine, 4. Department of Pediatrics, Federation of National Public Service Personnel Mutual Aid Associations Tachikawa Hospital, 5. Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences)

Keywords:

Epigenome editing,Prader-Willi syndrome,Hypothalamic organoid,Imprinting disorder

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