Presentation Information

[3P-051]A role of progranulin in maintaining lysosomal homeostasis through the lysosomal damage response

*Mai Makino1,2, Mitsuko Banja1, Takayuki Shima1,2, Takao Kiriyama3, Kazuha Nagae1, Tatsuya Kaminishi4, Hiroya Naruse5, Hiroyuki Ishiura6, Tatsushi Toda5,7, Tamotsu Yoshimori4, Yoshinori Tanaka8, Kazuma Sugie2,3, Shuhei Nakamura1,2 (1. Department of Biochemisty, Nara Medical University, Kashihara, Japan, 2. Center for Autophagy and Anti-Aging Research, Nara Medical University, Kashihara, Japan, 3. Department of Neurology, Nara Medical University, Kashihara, Japan, 4. Graduate School of Medicine, The University of Osaka, Suita, Japan, 5. Department of Neurology, The University of Tokyo, Tokyo, Japan, 6. Department of Neurology, Okayama University, Okayama, Japan, 7. National Center Hospital, National Center of Neurology and Psychiatry, Kodaira, Japan, 8. Department of Veterinary Medicine, Okayama University of Science, Imabari, Japan)

Keywords:

Lysosomal damage response,Neurodegenerative diseases,Lysosome,Autophagy

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