Presentation Information

[3P-375]Distinct recombinant tau fibril conformations induce divergent propagation and neurodegenerative phenotypes in a model mouse

*Rin Yanai1, Shingo Tamai2, Gen Matsumoto3, Takeharu Minamihisamatsu1, Shoko Uchida1, Yao Zhiwei1, Hiroshi Mizuma1,3, Ming-Rong Zhang1, Makoto Higuchi1,3,4, Masafumi Shimojo1,4, Motomasa Tanaka2, Naruhiko Sahara1,5,6 (1. National Institutes for Quantum Science and Technology, 2. RIKEN, 3. Osaka Metropolitan University Graduate School of Medicine, 4. Tohoku University Graduate School of Medicine, 5. Brain Research Institute, Niigata University, 6. Research Institute of Environmental Medicine, Nagoya University)

Keywords:

tau pathology,fibril structure,model mouse

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