Presentation Information
[3P-435]CRISPR screening in human iPSC-derived glioblastoma models reveals RNA-binding protein dependencies associated with TERT promoter mutations
*Christopher C. Chie1, Daisuke Kawauchi1, Shunichiro Miki1, Nicholas O. Stevers2, Joseph F. Costello2, Chun-Yuan Chen3, Gene W. Yeo3,4,5,6,7, Frank B. Furnari1 (1. Department of Medicine, Division of Regenerative Medicine, University of California-San Diego, San Diego, CA, USA, 2. Department of Neurological Surgery, University of California-San Francisco, San Francisco, CA, USA, 3. Sanford Stem Cell Institute, Innovation Center, San Diego, CA, USA, 4. Department of Cellular and Molecular Medicine, San Diego, CA, USA, 5. Sanford Laboratories for Innovative Medicines, San Diego, CA, USA, 6. Center for RNA Technologies and Therapeutics, San Diego, CA, USA, 7. Institute for Genomic Medicine, San Diego, CA, USA)
Keywords:
Glioblastoma,RNA-binding proteins,Telomeres,TERT
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