[3P] Poster

[3P-505] Human Striatal–Midbrain Assembloid model for GBA1-linked Parkinson’s disease and drug testing

*Junghyun Jo^1,2,3, Hoang-Dai Tran⁴, Min-Kyoung Shin^1,2, Muhammad Junaid^3,5, Eunho Cha^1,3, Sungsoo Lee^1,3, Sangyong Jung⁶, Ji Young Mun⁷, Bernd Kuhn⁸, Gordon Arbuthnott⁸, Su Bin Lim^3,5 (1. Department of Pharmacology, Ajou University School of Medicine, Republic of Korea, 2. Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Republic of Korea , 3. BK21 R&E Initiative for Advanced Precision Medicine, Department of Biomedical Sciences, Graduate School of Ajou University, Republic of Korea, 4. Department of Neurology, Massachusetts General Hospital and Harvard Medical School, USA, 5. Department of Biochemistry & Molecular Biology, Ajou University School of Medicine, Republic of Korea, 6. Department of Medical Science, College of Medicine, CHA University, Republic of Korea, 7. Neural Circuit Research Group, Korea Brain Research Institute, Republic of Korea, 8. Okinawa Institute of Science and Technology Graduate University, Japan)

Keywords:

Striatal–Midbrain assembloid,GBA1,Parkinson's disease,Drug testing

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