[3TS05m] DC, Disease

[3TS05m-02] Cryo-EM structure of P301L/S320F double-mutant tau filaments formed in mouse brains following peripheral AAV delivery

*Maria Kano^1,4, Taeko Kimura¹, Haruaki Yanagisawa², Lisa Tatsumi¹, Komei Yamashita¹, Asahi Sakai¹, Xinyi Li¹, Takaomi C Saido³, Takashi Saito², Sho Takatori¹, Masahide Kikkawa², Koji Yamanaka⁴, Taisuke Tomita¹ (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, 2. Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3. RIKEN Center for Brain Science, Saitama, Japan , 4. Research Institute of Environmental Medicine, Nagoya University, Aichi, Japan)

Keywords:

Alzheimer disease,Tau,Cryo-EM

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