[3TS05m] DC, Disease

[3TS05m-03] Parkinson's disease-linked PSAP mutations drive ER–Golgi–lysosome axis collapse through YKT6 dysfunction

*Kentaro Gejima¹, Yutaka Oji¹, Ryo Wakamori¹, Eriko Igami¹, Junji Yamaguchi², Mitsuhiro Kitagawa¹, Yoko Imamichi¹, Risa Nonaka^3,4, Masaya Imoto¹, Wado Akamatsu⁴, Taku Hatano¹, Nobutaka Hattori^1,5 (1. Department of Neurology, Juntendo University School of Medicine, 2. Laboratory of Morphology and Image Analysis, Juntendo University, 3. Juntendo University Faculty of Pharmacy , 4. Center of Genomic and Regeneration Medicine, Juntendo University, 5. Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science)

Keywords:

prosaposin,YKT6,glucocerebrosidase,golgi apparatus

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