[1P] Poster

[H. Disorders of Nervous Systems] Neurodegenerative Disorders

[1P-240] Microtubule dynamics dysregulation as a key driver of ALS pathogenesis

*HsiangHao Hu¹, Cing Lee², JhihTian Guo⁴, TingJhen Ou², Eric Hwang^1,2,3,5 (1. Inst Mol Med and Bioeng, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 2. Dept Biol Sci and Technol, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 3. Inst Bioinform and Syst Biol, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 4. Biomed Eng, Electr & Comput Eng Coll, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 5. Center for Intell Drug Syst and Smart Bio-devices, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan)

Keywords:

microtubule-targeting therapies,nuclear envelope abnormalities,axonal cargo transport defects,V-ATPase dysfunction

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