[2P] Poster

[H. Disorders of Nervous Systems] Neurodegenerative Disorders

[2P-231] The Therapeutic Potential of (R)-Carvedilol in Huntington’s Disease Through Enhancement of Autophagy-Lysosomal Pathway via GSK-3β Inhibition

*Tz Chuen Ju^1,2, Chih Yuan Cheng^3,4, Kai Po Chen^1,3 (1. Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan, 2. Doctoral Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan, 3. Department of Animal Science and Biotechnology, Tunghai University, Taichung, Taiwan, 4. Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan)

Keywords:

autophagy-lysosomal pathway (ALP),glycogen synthase 3β (GSK-3β),mutant huntingtin (mHTT),transcription factor binding to IGHM enhancer 3 (TFE3)

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