[3O10m-1] Motor System 1

[3O10m-1-3] Hyperactive isoform PI3K delta for long distance regeneration of adult rat corticospinal tract

*Kristyna Karova¹, Zuzana Polcanova¹, Lydia Knight¹, Stepanka Suchankova², Bart Nieuwenhuis³, Radovan Holota⁴, Vit Herynek⁵, Lucia Machova Urdzikova¹, Rostislav Turecek², Jessica C Kwok⁶, Joelle van den Heryk⁷, Joost Verhaagen⁷, Richard Eva⁸, James W Fawcett^1,3, Pavla Jendelova¹ (1. Dept of Neuroregeneration, Institute of Experimental Medicine, CASs, Prague, Czech Republic, 2. Dept of Auditory Neurosci, Institute of Experimental Medicine, CAS, Prague, Czech Republic, 3. John van Geest Centre for Brain Repair, Cambridge, UK, 4. Institute of Biology and Ecology, Safarik University Kosice, Kosice, Slovak Republic, 5. Center for Advanced Preclinical Imaging, First Faculty of Medicine, Charles University, Prague, Czech Republic, 6. School of Biomedical Sciences, University of Leeds, Leeds, UK, 7. Netherlands Institute for Neuroscience, Amsterdam, Netherlands, 8. Regeneration Group, The Wolfson Sensory Pain and Regeneration Centre, Kings College London, London, UK)

Keywords:

spinal cord regeneration,PI3Kdelta signalling,skilled paw reaching,electrophysiology

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