[4O10m-1] Glia 2 and others

[4O10m-1-3] Visualization of microglial phenotypic changes using P2Y12 receptor-targeted compound in two-photon imaging and MRI

*Yutaro Saito¹, Kenji Yatsuzuka², Takahiro Tsuji¹, Akira Sumiyoshi³, Kana Tsujimura², Hiroshi Nonaka⁴, Ayaka Takada⁵, Kanon Sato¹, Hatsumi Nakagawa¹, Rahadian Yudo Hartantyo¹, Hiroyuki Takuwa⁵, Hiroshi Yukawa^6,7, Itaru Hamachi⁸, Makoto Higuchi^9,10, Shigeki Kiyonaka², Hiroaki Wake^1,11 (1. Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, 2. Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, 3. Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4. Department of Material Chemistry, Graduate School of Engineering, Kyoto University, 5. Quantum Neuromapping and Neuromodulation Team, Quantum Life and Medical Engineering Group, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 6. Research Institute for Quantum and Chemical Innovation, Institutes of Innovation for Future Society, 7. Quantum Regenerative and Biomedical Engineering Team, Quantum Life and Medical Engineering Group, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 8. Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, 9. Advanced Neuroimaging Center, Institute for Medical Science, National Institutes for Quantum Science and Technology, 10. Department of Neuroetiology and Diagnostic Science, Osaka Metropolitan University Graduate School of Medicine, 11. Division of Multicellular Circuit Dynamics, National Institute for Physiological Sciences, National Institute of Natural Sciences)

Keywords:

microglia,P2RY12,MRI,two-photon imaging

Password required to view